Creatinolfosfat
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- CAS-Nr.
- 6903-79-3
- Bezeichnung:
- Creatinolfosfat
- Englisch Name:
- 1-(2-Hydroxyethyl)-1-methylguanidine dihydrogen phosphate
- Synonyma:
- COP;creatinol phosphate;CREATINOLO-PHOSPHATE;CARD16;Aplodan;Creatinolfosfat;CREATINOLFOSFATE;2-(1-Methylguanidino);Creatinol Phosphate >Creatinol-O-Phosphate(COP)
- CBNumber:
- CB6314530
- Summenformel:
- C4H12N3O4P
- Molgewicht:
- 197.13
- MOL-Datei:
- 6903-79-3.mol
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Creatinolfosfat Eigenschaften
- Schmelzpunkt:
- 244 °C(dec.)
- Siedepunkt:
- 244°C(lit.)
- Dichte
- 1.65±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- pka
- 1.84±0.10(Predicted)
- Aggregatzustand
- powder to crystal
- Farbe
- White to Almost white
- InChI
- 1S/C4H12N3O4P/c1-7(4(5)6)2-3-11-12(8,9)10/h2-3H2,1H3,(H3,5,6)(H2,8,9,10)
- InChIKey
- FOIPWTMKYXWFGC-UHFFFAOYSA-N
- SMILES
- OP(OCCN(C)C(N)=N)(O)=O
- CAS Datenbank
- 6903-79-3(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
WGK 3 |
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| RTECS-Nr. |
MF3600500 |
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| HS Code |
2925.29.9000 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H332 |
Gesundheitssch?dlich bei Einatmen. |
Akute Toxizit?t inhalativ |
Kategorie 4 |
Warnung |
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P261, P271, P304+P340, P312 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Creatinolfosfat Chemische Eigenschaften,Einsatz,Produktion Methoden
Originator
Aplodan,Simes,Italy,1968
Manufacturing Process
In a reactor put 80 kg of polyphosphoric acid having the following
composition: H5P3O10 - 60%; (HPO3)6 - 10%; H4P2O7 - 15%; (HPO3)x - 10%;
total content in P2O5 about 83%; this is heated to about 160°C.
Then 360 kg of creatinol phosphate are added to the polyphosphoric acid;
continue to heat for about two hours under vacuum until the reaction water is
eliminated.
The molten mass is then poured into ethanol at 95°C, the solution cooled
down to 10°C and the precipitated product separated by centrifugation. The
resulting product is dissolved in the minimum quantity of warm water and the
solution poured into ethanol.
Thus 297 kg of the phosphoric ester of the creatinol are obtained having these
characteristics: MP 240°C to 243°C.
Therapeutic Function
Cardiotonic
Creatinolfosfat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Creatinolfosfat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 181)Lieferanten
6903-79-3(Creatinolfosfat)Verwandte Suche:
- 1-(2-hydroxyethyl)-1-methylguanidine dihydrogen phosphate
- CREATINOLFOSFATE
- CREATINOLO-PHOSPHATEANDITSSODIUMSALT
- 1-[2-(Phosphonooxy)ethyl]-1-methylguanidine
- Aplodan
- 2-(1-Methylguanidino)ethyl dihydrogen phosphate
- APLODAN [TRADE], CREATINOLFOSFATE [INN]
- Guanidine,N-Methyl-N-[2-(phosphonooxy)ethyl]-
- ANTI-COP1(N-TERMINAL) antibody produced in rabbit
- CARD only domain-containing protein 1
- CARD16
- Caspase recruitment domain-containing protein 16
- 2-(1-Methylguanidino)
- 2-[carbamimidoyl(methyl)amino]ethyl dihydrogen phosphate
- Creatinol Phosphate >
- [2-(N-methylcarbamimidamido)ethoxy]phosphoni c acid
- Creatinolfosfat
- Creatinol-O-Phosphate(COP)
- Creatinolfosfate, Creatinol Phosphate
- 2-[[Amino(imino)methyl](methyl)amino]ethyl dihydrogen phosphate
- COP
- CREATINOLO-PHOSPHATE
- creatinol phosphate
- 6903-79-3
- C4H12N3O4P
