Hexamethoniumbromid
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- CAS-Nr.
- 55-97-0
- Bezeichnung:
- Hexamethoniumbromid
- Englisch Name:
- HEXAMETHONIUM BROMIDE
- Synonyma:
- HEXAMETHONIUM DIBROMIDE;N1,N1,N1,N6,N6,N6-hexamethylhexane-1,6-diaminium bromide;hexameton;vegolysen;vegolysin;esametina;gangliostat;Methobromine;simpatoblock;hexoniumdibromide
- CBNumber:
- CB6429850
- Summenformel:
- C12H30Br2N2
- Molgewicht:
- 362.19
- MOL-Datei:
- 55-97-0.mol
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Hexamethoniumbromid Eigenschaften
- Schmelzpunkt:
- ~285 °C (dec.)
- storage temp.
- Inert atmosphere,Room Temperature
- L?slichkeit
- Water (Slightly)
- Aggregatzustand
- Crystalline Powder and Agglomerates
- Farbe
- White
- PH
- pH (20g/l, 25℃) : 4.5～6.5
- Wasserl?slichkeit
- H2O: 100mg/mL
- Merck
- 14,4688
- BRN
- 3715749
- InChI
- InChI=1S/C12H30N2.2BrH/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2
- InChIKey
- FAPSXSAPXXJTOU-UHFFFAOYSA-L
- SMILES
- C(CCCCC[N+](C)(C)C)[N+](C)(C)C.[Br-].[Br-]
- CAS Datenbank
- 55-97-0(CAS DataBase Reference)
- EPA chemische Informationen
- 1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, bromide (1:2) (55-97-0)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
22-24/25 |
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| WGK Germany |
2 |
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| RTECS-Nr. |
BQ8575000 |
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| TSCA |
TSCA listed |
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| HS Code |
29239000 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H370 |
Sch?digt die Organe. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 1 |
Achtung |
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P260, P264, P270, P307+P311, P321,P405, P501 |
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| Sicherheit |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Hexamethoniumbromid Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Hexamethonium is a peripherally-acting nondepolarizing neuromuscular blocking agent that acts as an antagonist of nicotinic acetylcholine receptors (nAChRs). It decreases acetylcholine release induced by carbamoylcholine in isolated cat superior cervical ganglion when used at concentrations of 27.4 and 54.8 μg/ml. It also decreases mean arterial pressure in unanesthetized rats when administered at a dose of 40 mg/kg. Intraventricular administration of hexamethonium (18 ng, i.c.v.) induces signs of nicotine abstinence, including shaking, writhing, and chewing in nicotine-dependent rats. Formulations containing hexamethonium were previously used in the treatment of hypertension.
Chemische Eigenschaften
White crystalline powder and agglomerates
Verwenden
Hexamethonium bromide has been used:
- as an autonomic ganglia-blocking agent to study its effects on whisker movement in rats
- as a nicotinic receptor antagonist to study its effects on antigen-induced arthritis (AIA) progression in mice
- as a non-selective ganglionic nicotinic acetylcholine receptor (nAChR) antagonist to study its effects on cytisine-induced autonomic cardiovascular responses in mice
Hexamethoniumbromid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Hexamethoniumbromid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 238)Lieferanten
55-97-0(Hexamethoniumbromid)Verwandte Suche:
- gangliostat
- hexamethioniumbromide
- hexamethylenebis(trimethyl-ammoniudibromide
- hexameton
- hexoniumdibromide
- simpatoblock
- Methobromine
- Hexamethonium bromide,Hexane-1,6-bis(trimethylammonium bromide), N,N,N,N′,N′,N′-Hexamethylhexamethylenediammonium dibromide
- Hexamethonium bromide purum, >=95.0% (AT)
- Hexamethylenebis(trimethylammonium Bromide)
Hexane-1,6-bis(trimethylammonium Bromide)
- 1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, bromide (1:2)
- Hexane-1,6-bis(trimethylammonium bromide), N,N,N,Nμ,Nμ,Nμ-Hexamethylhexamethylenediammonium dibromide
- Hexamethonium bromide ,98%
- HEXAMETHONIUM BROMIDE HYDRATE, 98+%
- vegolysen
- vegolysin
- 6-hexanediaminium,n,n,n,n’,n’,n’-hexamethyl-dibromide
- alpha,omega-bis(trimethylammonium)hexanedibromide
- esametina
- N,N,N,N',N',N'-HEXAMETHYLHEXAMETHYLENEDIAMMONIUM DIBROMIDE
- HEXANE-1,6-BIS(TRIMETHYLAMMONIUM BROMIDE)
- HEXAMETHYLENEBIS(TRIMETHYLAMMONIUM BROMIDE)
- HEXAMETHONIUM BROMIDE
- HEXAMETHONIUM BROMIDE USP/EP/BP
- trimethyl-[6-(trimethylazaniumyl)hexyl]azanium
- Hexamethonium bromide, nicotinic receptor blocker
- Hexamethonium Bromide, 10 mM in DMSO
- HEXAMETHONIUM DIBROMIDE
- N1,N1,N1,N6,N6,N6-hexamethylhexane-1,6-diaminium bromide
- 55-97-0
- C12H32Br2N2O
- C12H30Br2N2
- C12H30N22Br
- C12H30Br2N2xH2O
- CH33NBrCH26NBrCH33
- BioChemical
- Ammonium Salts
- Cell Biology
- Cell Signaling and Neuroscience
- Ammonium Bromides (Quaternary)
- Quaternary Ammonium Compounds
- Phase Transfer Catalysts
- Synthetic Reagents
- Ion Channels
- Ligand-Gated Ion Channels
- Nicotinic Acetylcholine Receptor Modulators
- Ammonium Bromides (Quaternary)
- Quaternary Ammonium Compounds
