Bosentan hydrate
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- CAS-Nr.
- 157212-55-0
- Englisch Name:
- Bosentan hydrate
- Synonyma:
- Bosentan monohydrate;CS-170;Bosetan;bosentan hydrate;Bosentan (200 mg);Bosentan (1076115);Bosentan hydrate USP/EP/BP;Bosentan Hydrate
See B675900;Bosentan Hydrate (Ro 47-0203);Tracleer, Bosentan monohydrate
- CBNumber:
- CB6547457
- Summenformel:
- C27H31N5O7S
- Molgewicht:
- 569.62934
- MOL-Datei:
- 157212-55-0.mol
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Bosentan hydrate Eigenschaften
- Schmelzpunkt:
- 114-118 °C
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO (Slightly), Methanol (Very Slightly, Heated)
- Aggregatzustand
- powder
- Farbe
- white to beige
- Merck
- 14,1353
- InChIKey
- SXTRWVVIEPWAKM-UHFFFAOYSA-N
- SMILES
- S(=O)(=O)(C1C=CC(=CC=1)C(C)(C)C)NC1=NC(C2=NC=CC=N2)=NC(OCCO)=C1OC1C=CC=CC=1OC.O
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
WGK 2 |
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| HS Code |
2935909550 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Aquatic Chronic 3
Repr. 2 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H412 |
Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gew?ssergef?hrdend |
Kategorie 3 |
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P273, P501 |
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| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
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Bosentan hydrate Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Bosentan hydrate has been used in cell viability assay. It has also been used as a positive control for calcium transient analysis.
Trademarks
Tracleer (Actelion).
Biochem/physiol Actions
Bosentan is an endothelin receptor antagonist. Endothelin is a potent vasoconstrictor, making antagonists of clinical interest for the treatment of conditions associated with vasospasm, such as subarachnoid hemorrhage (SAH) and hypertension. Bosentan is a dual endothelin receptor antagonist effective in the treatment of pulmonary arterial hypertension (PAH), the first of the class to make it to market. Bosentan is an orally available, competitive antagonist of both the ETA and ETB receptor subtypes with a Ki of 4.7 nM for ETA and a Ki of 95 nM for ETB.
Bosentan hydrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Bosentan hydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 391)Lieferanten
157212-55-0()Verwandte Suche:
- Bosetan
- 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfona
- 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-Methoxyphenoxy)-2-(pyriMidin-2-yl)pyriMidin-4-yl]benzene-1-sulfonaMide
- Bosentan Hydrate
See B675900
- Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-, hydrate (1:1)
- Bosentan (200 mg)
- bosentan hydrate
- 4-(1,1-dimethylethyl)-n-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)(2,2'-bipyrimidin)-4-yl)benzenesulfonamide monohydrate
- CS-170
- 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]benzene-1-sulfonamide hydrate
- Bosentan hydrate USP/EP/BP
- Bosentan Hydrate (Ro 47-0203)
- 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide hydrate[Ro-47-0203 Hydrate
- Bosentan MonohydrateQ: What is
Bosentan Monohydrate Q: What is the CAS Number of
Bosentan Monohydrate Q: What is the storage condition of
Bosentan Monohydrate Q: What are the applications of
Bosentan Monohydrate
- Bosentan HydrateQ: What is
Bosentan Hydrate Q: What is the CAS Number of
Bosentan Hydrate Q: What is the storage condition of
Bosentan Hydrate Q: What are the applications of
Bosentan Hydrate
- Bosentan (1076115)
- Tracleer, Bosentan monohydrate
- Bosentan Monohydrate/Bosentan Hydrate
- 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide hydrate
- Bosentan (hydrate), 10 mM in DMSO
- BOSENTAN MONOHYDRATE (NON-STERILE DRUG SUBSTANCE)
- 4-(1,1-dimethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidine]-4-yl]benzenesulfonylamide
- Bosentan monohydrate
- 157212-55-0
- C27H29N5O6SH2O
- 9N5O6SH2O
- C27H31N5O7S
- C27H29N5O6S2O
- Inhibitors
- API
- Heterocyclic Compounds
