Almitrin Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Respiratory stimulant.
Definition
ChEBI: A triamino-1,3,5-triazine compound having allylamino substituents at the 2- and 4-positions and a 4-(bis(p-fluorophenyl)methyl)-1-piperazinyl group at the 6-position.
Weltgesundheitsorganisation (WHO)
Peripheral neuropathy has been reported in a few patients
receiving almitrine for long periods. The indications for treatment have consequently been restricted in the Federal Republic of Germany. Some other
countries have advised doctors to maintain patients under close supervision
throughout treatment and to restrict dosage to two out of every three months.
Pharmakologie
Almitrine, like doxapram, increases the rate and depth of respiration. In addition, it is
believed that it redistributes pulmonary blood circulation, increasing it in alveoli, which
leads to relatively better pulmonary ventilation. It has a more prolonged effect than
doxapram.
Sicherheitsprofil
Poison by intraperitoneal andintravenous routes. When heated to decomposition itemits very toxic fumes of F and NOx.
Almitrin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
