HISPIDULIN
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- CAS-Nr.
- 1447-88-7
- Englisch Name:
- HISPIDULIN
- Synonyma:
- Dinatin;HISPIDULIN;Hispedulin;Hispidulin-RM;Methoxyapigenin;Hispidulin, >99%;6-Methoxyapigenin;Hispidulin(Dinatin);6-Methylscutellarein;Hispidulin - Bio-X ?
- CBNumber:
- CB6723941
- Summenformel:
- C16H12O6
- Molgewicht:
- 300.26
- MOL-Datei:
- 1447-88-7.mol
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HISPIDULIN Eigenschaften
- Schmelzpunkt:
- 291-292 °C
- Siedepunkt:
- 601.5±55.0 °C(Predicted)
- Dichte
- 1.512±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- L?slichkeit
- DMSO: soluble20mg/mL, clear
- pka
- 6.51±0.40(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to beige
- InChI
- InChI=1S/C16H12O6/c1-21-16-11(19)7-13-14(15(16)20)10(18)6-12(22-13)8-2-4-9(17)5-3-8/h2-7,17,19-20H,1H3
- InChIKey
- IHFBPDAQLQOCBX-UHFFFAOYSA-N
- SMILES
- C1(C2=CC=C(O)C=C2)OC2=CC(O)=C(OC)C(O)=C2C(=O)C=1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
DJ2996000 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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HISPIDULIN Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Hispidulin has been used as a calibration standard:
- in high-performance liquid chromatography (HPLC) for quantification of Clerodendrum petasites flavonoids
- in liquid chromatography/electrospray ionization mass spectrometry (LC/ESI-MS) analysis
- in reverse-phase high-performance liquid chromatography with a diode-array detector (HPLC-DAD) and high-performance thin-layer chromatography (HPTLC)
Definition
ChEBI: A monomethoxyflavone that is scutellarein methylated at position 6.
Allgemeine Beschreibung
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biologische Aktivit?t
Partial positive allosteric modulator at the benzodiazepine receptor (IC 50 = 1.3 μ M for inhibition of flumazenil binding); natural sage flavone. Stimulates GABA-induced chloride currents in Xenopus oocytes expressing α 1 α 2-, α 3-, α 5- or α 6- β 2 γ 2S GABA A receptors. Brain penetrant; oral administration reduces seizures in a gerbil model of epilepsy. Also has antifungal, antiproliferative, antioxidant and antithrombotic properties.
HISPIDULIN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
HISPIDULIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 242)Lieferanten
1447-88-7()Verwandte Suche:
- SCUTELLAREIN 6-METHYL ETHER
- 4',5,7-Trihydroxy-6-methoxyflavone
- 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
- 6-Methoxyapigenin
- 6-Methylscutellarein
- Hispidulin(Dinatin)
- Methoxyapigenin
- Hispedulin
- HISPIDULIN
- Hispidulin, >99%
- 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-
- 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one
- Hispidulin-RM
- Hispidulin, 10 mM in DMSO
- Hispidulin - Bio-X ?
- Dinatin
- http://www.hezefdc.com/ProdSupplierGNCB6723941.htm
- 1447-88-7
- Miscellaneous Natural Products
