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β-Elemonic Acid

β-Elemonic Acid Struktur
28282-25-9
CAS-Nr.
28282-25-9
Englisch Name:
β-Elemonic Acid
Synonyma:
elemonic acid;BETA-ELEMONIC ACID;Elemadienonic acid;β-Elemonic;β-Elemonic;Beta-EleMonic;β-deMonic acid;β-demonic-acid;B-ELEMONIC ACID;β-Elemonic acid
CBNumber:
CB6737997
Summenformel:
C30H46O3
Molgewicht:
454.68
MOL-Datei:
28282-25-9.mol

β-Elemonic Acid Eigenschaften

Schmelzpunkt:
224-225°C
Siedepunkt:
565.2±50.0 °C(Predicted)
Dichte
1.07
storage temp. 
2-8°C
L?slichkeit
DMF: 30 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 5 mg/ml; Ethanol: 5 mg/ml
Aggregatzustand
A crystalline solid
pka
4.65±0.10(Predicted)
Farbe
White to off-white
InChIKey
XLPAINGDLCDYQV-XUWOXAENSA-N
SMILES
C\C(C)=C\CC[C@@H]([C@@H]1CC[C@]2(C)C3=C(CC[C@@]12C)[C@@]4(C)CCC(=O)C(C)(C)[C@@H]4CC3)C(O)=O

Sicherheit

WGK Germany  WGK 3
Speicherklasse 13 - Non Combustible Solids

β-Elemonic Acid Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

β-Elemonic acid is a triterpene isolated from Boswellia (Burseraceae) that exhibits anticancer activity. It inhibits growth of non-small cell lung cancer (NSCLC) A549 cells (IC50 = 6.92 μM) in vitro. β-Elemonic acid induces apoptosis and cytotoxicity in A549 cells in a dose-dependent manner but has no effect on normal epithelial WI-38 cells. It inhibits phosphorylation of p42/44, MAPK/JNK, and p38 and induces production of reactive oxygen species (ROS) and COX-2 expression in vitro. β-Elemonic acid also inhibits prolyl endopeptidase (IC50 = 39.74 μM) in vitro.

Verwenden

β-Elemonic Acid inhibits cell proliferation of human lung adenocarcinoma A549 cells and role of MAPK, ROS activation and glutathione depletion. Elemonic acid is also a Pin1 inhibitors.

β-Elemonic Acid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


β-Elemonic Acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 184)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
Chengdu Greenpure Biopharma CO.,Ltd
18283602253; +8618283602253
jancyzheng@gcgreenpure.com China 954 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083
scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897
sales@biopurify.com China 4616 58
Shanghai Standard Technology Co., Ltd.
18502101150
ft-sales@nature-standard.com CHINA 1923 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29792 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879
sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
Hubei Ipure Biology Co., Ltd
+8613367258412
ada@ipurechemical.com China 10236 58
Aktin Chemicals, Inc.
028-85159085
info@aktinchem.com CHINA 1025 58

28282-25-9()Verwandte Suche:


  • Beta-EleMonic
  • 3-OXOTIRUCALLA-8,24-DIEN-21-OIC ACID
  • β-deMonic acid
  • (13α,14β,17α,20S)-3-Oxolanosta-8,24-dien-21-oic acid
  • B-ELEMONIC ACID
  • (13α,14β,17α,20S)-3-Oxo-5α-lanosta-8,24-dien-21-oic acid
  • (20S)-3-Oxoeupha-8,24-diene-21-oic acid
  • 3-Oxo-5α-tirucalla-8,24-dien-21-oic acid
  • (13alpha,14beta,17alpha,20S)-3-Oxolanosta-8,24-dien-21-oic acid
  • 3-Ketotirucalla-8,24-dien-21-oic acid
  • 3-Oxo-8,24-tirucalledien-21-oic acid
  • 3-Oxotirucallenoic acid
  • 3-Oxotirucallic acid
  • β-Elemonic acid
  • β-Elemonic acid, 98%, from Canarium album (Lour.) Raeusch.
  • β-Elemonic
  • Lanosta-8,24-dien-21-oic acid, 3-oxo-, (13α,14β,17α,20S)-
  • β-demonic-acid
  • β-Elemonic Acid, 10 mM in DMSO
  • β-Elemonic
  • β-elemonic acid
  • β-Elemonic Acid (Standard)
  • BETA-ELEMONIC ACID
  • Elemadienonic acid
  • elemonic acid
  • 28282-25-9
  • C30H46O3
  • Triterpenoids
  • Tri-Terpenoids
  • reagent
  • standard substance
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