4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE
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- CAS-Nr.
- 84905-80-6
- Englisch Name:
- 4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE
- Synonyma:
- SW-58;SWF-58;4-CHLORO-5H-PYRROLO[3;6-chloro-9-deaza-7H-puri;4-Chloro-5H-pyrrolo[3,2-d...;4-chloro-5H-pyrrolo[2,3-c]pyridine;4-chloro-1H-pyrrolo[3,2-d]pyriMidine;5H-Pyrrolo3,2-dpyrimidine, 4-chloro-;4-Chloro-5H-pyrrol[3,2-d] pyrimidine;4-CHLORO-5H-PYROLO-[3,2-d]PYRIMIDINE
- CBNumber:
- CB6771371
- Summenformel:
- C6H4ClN3
- Molgewicht:
- 153.57
- MOL-Datei:
- 84905-80-6.mol
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4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Eigenschaften
- Schmelzpunkt:
- 186-188 °C (decomp)(Solv: water (7732-18-5); ethanol (64-17-5))
- Siedepunkt:
- 325.9±22.0 °C(Predicted)
- Dichte
- 1.531±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Aggregatzustand
- solid
- pka
- 11.58±0.40(Predicted)
- Farbe
- Off-white
- InChI
- InChI=1S/C6H4ClN3/c7-6-5-4(1-2-8-5)9-3-10-6/h1-3,8H
- InChIKey
- ZGJDDWOXVGDTSP-UHFFFAOYSA-N
- SMILES
- C1=NC(Cl)=C2NC=CC2=N1
4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
4-Chloro-5H-pyrrolo[3,2-d]pyrimidine is a purine analog that inhibits the growth of bacteria by binding to the enzyme DNA gyrase. It has been shown to be effective against staphylococcus and Mycobacterium tuberculosis.
Verwenden
4-Chloro-5H-pyrrolo[3,2-d]pyrimidine is a chlorinated pyrrolopyrimidine used in the preparation of compounds with antibacterial and antitumor activities.
Application
4-Chloro-5H-pyrrolo[3,2-d]pyrimidine binds to the enzyme DNA gyrase and prevents it from breaking down the bacterial DNA. This drug also has antimycobacterial activity due to its ability to bind to the enzyme RNA polymerase.
4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 224)Lieferanten
84905-80-6()Verwandte Suche:
- 4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE
- 4-Chloro-5H-pyrrol[3,2-d] pyrimidine
- 5H-Pyrrolo3,2-dpyrimidine, 4-chloro-
- 4-chloro-5H-pyrrolo[2,3-c]pyridine
- 4-Chloro-5H-pyrrolo[3,2-d...
- 6-chloro-9-deaza-7H-purine, 4-chloro-3H,5H-pyrrolo[3,2-d]pyriMidine, 4-Chloropyrrolo<3,2-d>pyriMidine
- 4-chloro-1H-pyrrolo[3,2-d]pyriMidine
- 6-chloro-9-deaza-7H-puri
- 4-CHLORO-5H-PYRROLO[3
- SW-58
- SWF-58
- 4-CHLORO-5H-PYROLO-[3,2-d]PYRIMIDINE
- 84905-80-6
- 4905-80-6
- Heterocycle-Pyrimidine series
- CHIRAL CHEMICALS
- Heterocycles series
