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4'-tert-Butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenon

4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone Struktur
43076-30-8
CAS-Nr.
43076-30-8
Bezeichnung:
4'-tert-Butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenon
Englisch Name:
4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone
Synonyma:
Terfenadine EP Impurity A;Terfenadine impurity A CRS;Terfenadine USP Related Compound A;4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone;1-(4-TERT-BUTYLPHENYL)-4-[4-(ALPHA-HYDROXYBENZHYDRYL)PIPERIDINO]BUTAN-1-ONE;1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-one;1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-one;1-Butanone, 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-;1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-one (Terfenadone)
CBNumber:
CB6884031
Summenformel:
C32H39NO2
Molgewicht:
469.66
MOL-Datei:
43076-30-8.mol

4'-tert-Butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenon Eigenschaften

Schmelzpunkt:
175 °C
Siedepunkt:
624.5±55.0 °C(Predicted)
Dichte
1.082±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
Chloroform (Slightly), Methanol (Slightly)
pka
13.32±0.29(Predicted)
Major Application
pharmaceutical (small molecule)
InChIKey
YCADFOXVGUGHRV-UHFFFAOYSA-N
SMILES
N2(CCC(CC2)C(O)(c4ccccc4)c3ccccc3)CCCC(=O)c1ccc(cc1)C(C)(C)C

Sicherheit

WGK Germany  WGK 3
Speicherklasse 11 - Combustible Solids

4'-tert-Butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenon Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Terfenadone, is the first nonsedating antihistamine for the treatment of allergic rhinitis. It is also the derivative of Terfenadine (T114500). Terfenadine, has been also identified to be an inhibitor of human CD81-receptor HCV-E2 interaction.

4'-tert-Butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenon Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Terfenadin

4'-tert-Butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenon Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 11)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81139210 +86-18192627656
 1059@dideu.com China 3587 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532
 jkinfo@jkchemical.com China 96815 76
Shanghai Macklin Biochemical Co.,Ltd. 15221275939; 15221275939
 shenlinxing@macklin.cn China 15781 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
 sales@rrkchem.com China 57422 58
LGC Science (Shanghai) Ltd. 17717235263
 fan.yang@lgcgroup.com China 18217 58
Merck KGaA 21-20338288
ordercn@merckgroup.com China 6038 58
Santa Cruz Biotechnology Inc 021-60936350
scbt@scbt.com China 6530 58

43076-30-8(4'-tert-Butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenon)Verwandte Suche:

  • 4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone
  • 1-(4-TERT-BUTYLPHENYL)-4-[4-(ALPHA-HYDROXYBENZHYDRYL)PIPERIDINO]BUTAN-1-ONE
  • 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-one
  • 1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-one
  • Terfenadine impurity A CRS
  • 1-Butanone, 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-
  • Terfenadine USP Related Compound A
  • Terfenadine EP Impurity A
  • 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-one (Terfenadone)
  • 43076-30-8
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