一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Dapoxetine hydrochloride

Dapoxetine hydrochloride Struktur
129938-20-1
CAS-Nr.
129938-20-1
Englisch Name:
Dapoxetine hydrochloride
Synonyma:
DAPOXETINE HCL;Priligy;Dapoxetin HCl;DL-Dapoxteine HCL;Dapoxetine HCL (Priligy);LY-21044;LY-210448;Dapoxetine HCI;Rimonabant 75000;Dapoxetine HCL-IHS
CBNumber:
CB7104314
Summenformel:
C21H24ClNO
Molgewicht:
341.88
MOL-Datei:
129938-20-1.mol

Dapoxetine hydrochloride Eigenschaften

Schmelzpunkt:
175-1790C
alpha 
D +135.78° (c = 2.18 in methanol)
storage temp. 
room temp
L?slichkeit
DMSO: ≥20mg/mL
Aggregatzustand
powder
Farbe
white
Optische Rotation
[α]/D +125 to +135°, c = 1 in methanol
Merck 
14,2821
InChI
InChI=1/C21H23NO.ClH/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21;/h3-14,20H,15-16H2,1-2H3;1H/t20-;/s3
InChIKey
IHWDIQRWYNMKFM-OZYVVJTJNA-N
SMILES
O(C1=CC=CC2C=CC=CC1=2)CC[C@@H](C1C=CC=CC=1)N(C)C.Cl |&1:13,r|
CAS Datenbank
129938-20-1(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn,N
R-S?tze: 22-36-50/53
S-S?tze: 36-60-61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
HS Code  29221990
Speicherklasse 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Aquatic Chronic 4
Eye Irrit. 2
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H413 Kann für Wasserorganismen sch?dlich sein, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 4
Sicherheit
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Dapoxetine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Dapoxetine hydrochloride, belonging to the class of SSRIs, was the first drug originally approved for the on-demand treatment of men with PE by seven European countries in 2008.
Premature ejaculation (PE) is the most common male sexual dysfunction. Dapoxetine is a short-acting SSRI. It is differentiated from the existing SSRI treatments for PE by the fact that it can be administered on an as-needed basis. In healthy subjects, dapoxetine is rapidly absorbed after oral administration with a peak plasma concentration (Tmax) occurring between 1.4 and 2h.

Chemische Eigenschaften

Dapoxetine hydrochloride is a white to slightly yellow powder. It is freely soluble in methanol, propylene glycol, some organic solvents (eg. N,N-dimethylformamide) , slightly soluble in ethanol and almost insoluble in water. It is a BCSI class II compound, and poor solubility is a key factor affecting the difference in clinical efficacy. Dapoxetine hydrochloride exists in various crystal forms, the solubility of different crystal forms is quite different, and there is a phenomenon of phase and transformation between crystal forms.

Verwenden

Dapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation in men. Premature ejaculation (PE) is the most common male sexual disorder, estimated to affect up to 30% of men.

Allgemeine Beschreibung

Dapoxetine ((+)-(S)-N,N-dimethyl-(α)-[2(1naphthal enyloxy)ethyl]-benzenemethanamine hydrochloride) possess a similar structure as that of fluoxetine.

Mode of action

The mechanism of action of dapoxetine in premature ejaculation is presumed to be linked to the inhibition of neuronal reuptake of serotonin and the subsequent potentiation of the neurotransmitter's action at pre- and post-synaptic receptors. Dapoxetine is a centrally-acting SSRI that modulates serotonin levels in relevant areas such as the lateral paragigantocellular nucleus through inhibition of the serotonin transporter (SERT). This compound also decreases peak amplitude and accelerates the decay rate of current inactivation in a variety of voltage-gated K+ channels.

Dapoxetine hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Dapoxetine hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 663)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Wuhan Nutra Biotechnology Co.,Ltd
+8617786394783
nutrabiotech@outlook.com China 300 58
Hubei Chuyunshun Biotechnology Co., Ltd.
+86-15926415536
hbcyssw@163.com China 160 58
Guangzhou Tosun Pharmaceutical Ltd
+86-020-61855200-902 +8618124244216
info@upharm.cn China 897 58
Xi an Biohorlden Industry Trade Co Ltd
+86-18829283179 +86-13636819721
sales@horlden.com China 334 58
Jinan Hong Kongda Chemical Co.,LTD
+86-18753193522 +86-18753193522
sales@hkdchem.com China 97 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055
Sibel@chuanghaibio.com China 8738 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971
deasea125996@gmail.com China 2472 58
qingdao future trading Co., Ltd
+86-13335044410
cui56813@163.com China 110 58
Shandong Huisheng Import & Export Co., Ltd.
+86-13176845580
da@zhongda-biotech.com China 232 58
Anhui Zhongda Biotechnology Co., Ltd
+8619956560829
justine@zhongda-biotech.com China 286 58

129938-20-1()Verwandte Suche:


  • Dapoxetine hydrochloride (1S)-N,N-Dimethyl-3-naphthalen-1-yloxy-1-phenyl-propan-1-amine hydrochloride
  • S-(+)-N,N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride, LY-210448 hydrochloride
  • Mixed spin Dapoxetine
  • (1s)-n,n-dimethyl-3-naphthalen-1-yloxy-1-phenyl-propan-1-amine hydrochloride
  • Rimonabant 75000
  • (aS)-N,N-Dimethyl-a-[2-(1-naphthalenyloxy)ethyl]benzenemethanamine
  • LY-21044
  • ((S)-(+)-N,N-Dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride)
  • (S)-(+)--N,N-Dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine
  • Dapoxetine hydrochloride
  • (aS)-N,N-Dimethyl-α-[2-(1-naphthalenyloxy)ethyl]benzenemethanamine
  • LY-210448
  • Dapoxetine hcl for R&D
  • naphthalen-1-yloxy-1-phenyl-propan-1-amine hydrochloride
  • (S)-Dapoxetine hydrochloride
  • (αS)-N,N-DiMethyl-α-[2-(1-naphthalenyloxy)ethyl]benzeneMethanaMine
  • Dapoxetine hydrochloride|S1869
  • Dapoxetine hydrochloride(Priligy)
  • N,N-DiMethyl-1-phenyl-3-(1-naphthalenyloxy)propanaMinehydrochloride
  • (S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride
  • D-(+)N,N-diMethyl-3-(naphthalen-1-yloxy)
  • (αS)- N,N-dimethyl-α-[2-(1-naphthalenyloxy)ethyl]-benzenemethanamine, hydrochloride (1:1)
  • (6R,7R)-7-Amino-8-oxo-3-(1-propenyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidDapoxetine hydrochloride
  • Benzenemethanamine, N,N-dimethyl-α-[2-(1-naphthalenyloxy)ethyl]-, hydrochloride, (S)-
  • (S)-N,N-DIMETHYL-Α-[2-(1-NAPHTHALENY-LOXY)ETHYL]BENZENEMETHANAMINE HYDROCHLORIDE
  • Dapoxetine hydrochloride, 98%, a short-acting novel selective serotonin reuptake inhibitor
  • DapoxetineHydrochloride>
  • Dapoxetine hydrochloride,>98%
  • Dapoxetine Hydrochlorid Salt
  • (S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenylpropylamine Hydrochloride
  • (S)-N,N-Dimethyl-alpha-[2-(1-naphthyloxy)ethyl]benzylamine Hydrochloride
  • Dapoxetine hydrochloride USP/EP/BP
  • Hydrochloride Dapoxetine
  • Right-handed poxetine
  • Dapoxetine HCI
  • Dapoxetine HCL-IHS
  • Dapoxetine HCl (LY-210448 HCl)
  • Dapoxetine HydrochlorideQ: What is Dapoxetine Hydrochloride Q: What is the CAS Number of Dapoxetine Hydrochloride Q: What is the storage condition of Dapoxetine Hydrochloride Q: What are the applications of Dapoxetine Hydrochloride
  • Dapoxetine/Dapoxetine HCl/Dapoxetine hydrochloride
  • LY-210448 hydrochloride
  • PRILIGY;LY-210448 HYDROCHLORIDE
  • (S)-N,N-dimethyl-3-
  • D-Dapoxetine Hydrochloride
  • Dapoxetin HCl
  • Dapoxetine HCL (Priligy)
  • DAPOXETINE HYDROCHLORIDE CHEMISTRY PURE 98.5% HPLC
  • DL-Dapoxteine HCL
  • Dapoxetine / Priligy
  • Dapoxetine HCl Powder
  • Dapoxetine Hydrochloride, ≥ 98.0%
  • LY-210448|||LY-210448 hydrochloride|||Dapoxetine HCl|||Priligy
  • Dapoxetine Hydrochloride B
  • Dapoxetine Hydrochloride C
  • Dapoxetine hydrochloride, 10 mM in DMSO
  • Dapoxetine hydrochloride - Bio-X ?
  • Dapoxetine hydrochlorid
  • (S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropylamine HCl
  • DAPOXETINE HCL
Copyright 2019 ? ChemicalBook. All rights reserved
三都| 英吉沙县| 桑日县| 大新县| 左权县| 马公市| 涞源县| 织金县| 六枝特区| 六枝特区| 阳原县| 措勤县| 仪征市| 白玉县| 离岛区| 固安县| 彝良县| 常熟市| 郁南县| 台东县| 永顺县| 湟中县| 聊城市| 平定县| 内黄县| 简阳市| 台南县| 永清县| 柳林县| 涿鹿县| 云安县| 安徽省| 南城县| 大石桥市| 琼海市| 石狮市| 高青县| 藁城市| 榆社县| 桦南县| 东光县|