Dehydrocostus lactone
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- CAS-Nr.
- 477-43-0
- Englisch Name:
- Dehydrocostus lactone
- Synonyma:
- DEHYDROCOSTUSLACTONE;EPILIGULYL OXIDE;DEHYDROCOSTUNOLIDE;ehydrocostuslactone;dehydrocostiolactone;Costus lactone, dehydro-;Dehydrocostus lactone-RM;DEHYDROCOSTUS LACTONE hplc;Dehydrocostus lactone, >=98%;Dehydrocostuslactone Standard
- CBNumber:
- CB7106297
- Summenformel:
- C15H18O2
- Molgewicht:
- 230.3
- MOL-Datei:
- 477-43-0.mol
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Dehydrocostus lactone Eigenschaften
- Schmelzpunkt:
- 57.0 to 61.0 °C
- Siedepunkt:
- 140-143 °C(Press: 0.5 Torr)
- Dichte
- 1.09
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- L?slichkeit
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Geruch (Odor)
- nutty
- Optische Rotation
- [α]/D -14.0±3.0°, c = 1 in chloroform
- maximale Wellenl?nge (λmax)
- 206nm(MeOH)(lit.)
- InChI
- InChI=1S/C15H18O2/c1-8-4-7-12-10(3)15(16)17-14(12)13-9(2)5-6-11(8)13/h11-14H,1-7H2/t11-,12-,13-,14-/m0/s1
- InChIKey
- NETSQGRTUNRXEO-XUXIUFHCSA-N
- SMILES
- O1C(=O)C(=C)[C@]2([H])CCC(=C)[C@@]3([H])[C@@]([H])([C@@]12[H])C(=C)CC3
- LogP
- 1.480 (est)
- CAS Datenbank
- 477-43-0(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
24/25 |
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| WGK Germany |
WGK 3 |
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| HS Code |
29322090 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Skin Sens. 1 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
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P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P272 |
Kontaminierte Arbeitskleidung nicht au?erhalb des Arbeitsplatzes tragen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P333+P313 |
Bei Hautreizung oder -ausschlag: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
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Dehydrocostus lactone Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Dehydrocostus lactone is a natural sesquiterpene first isolated from costus root, which is used in traditional medicine. Dehydrocostus lactone has diverse anti-cancer properties in cells and animal models, causing cell cycle arrest, inducing apoptosis, diminishing multidrug resistance, and suppressing angiogenesis in cancer cells. It also has anti-inflammatory actions in cells, including the inhibition of signaling through STAT1 and STAT3.
Verwenden
Dehydrocostus lactone is the oil extracted from Saussurea lappa is used in perfumery and in the Orient for all kinds of diseases.
Definition
ChEBI: An organic heterotricyclic compound and guaianolide sesquiterpene lactone that is acrylic acid which is substituted at position 2 by a 4-hydroxy-3,8-bis(methylene)decahydoazulen-5-yl group and in which the hydroxy group and the carboxy group have undergone
formal condensation to afford the corresponding gamma-lactone.
Kontakt-Allergie
A guaianolide sesquiterpene lactone extracted from costus oil. It is one of the components of Lactone mix, with costunolide and alantolactone, used to detect Compositae-sensitive patients.
Dehydrocostus lactone Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Dehydrocostus lactone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 288)Lieferanten
477-43-0()Verwandte Suche:
- EPILIGULYL OXIDE
- DEHYDROCOSTUS LACTONE hplc
- (3aS,6aR,9aR,9bS)-Decahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one
- DEHYDROCOSTUNOLIDE
- Azuleno[4,5-b]furan-2(3H)-one,decahydro-3,6,9-
- Costus lactone, dehydro-
- tris(methylene)-,(3aS,6aR,9aR,9bS)-
- (3aS)-3,6,9-Tris(methylene)-2,3,3a,4,5,6,6aβ,7,8,9,9aβ,9bα-dodecahydroazuleno[4,5-b]furan-2-one
- (3aS,6aβ,9aβ,9bα)-Dodecahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2-one
- 3aβ,4,5,6,6aβ,7,8,9,9aβ,9bα-Decahydro-3,6,9-trismethyleneazuleno[4,5-b]furan-2(3H)-one
- (3aS,6aR,9aR,9bS)-3,6,9-trimethylene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one
- (3aS,6aR,9aR,9bS)-3,6,9-trimethylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one
- [3aS-(3aalpha,6aalpha,9aalpha,9bbeta)]-Decahydro-3,6,9-tris(methylene)-azuleno[4,5-b]furan-2(3H)-one
- Dehydro-costus lactone (6CI,7CI)
- Guaia-4(15),10(14),11(13)-trien-12-oic acid, 6alpha-hydroxy-, gamma-lactone
- Dehydrocostus lactone, >=98%
- Dehydrocostus Lactone 477-43-0
- Dehydrocostuslactone, 98%, from Common Vladimiria Root
- Dehydrocostus Lactone ((-)-Dehydrocostus lactone
- Dehydrocostuslactone Standard
- Azuleno[4,5-b]furan-2(3H)-one, decahydro-3,6,9-tris(methylene)-, (3aS,6aR,9aR,9bS)-
- ehydrocostuslactone
- (3aS,6aR,9aR,9bS)-3,6,9-Trimethylenedecahydroazuleno[4,5-b]furan-2(9bH)-one
- (3aS,6aR,9aR,9bS)-3,6,9-Trimethylenedecahydroazuleno[4,5-b]furan-2(3H)-one
- dehydrocostiolactone
- Dehydrocostus lactone-RM
- Dehydrocostus lactone, Cell proliferation inhibitor
- DEHYDROCOSTUSLACTONE
- 477-43-0
- 447-43-0
- C15H18O2
- Sesquiterpenoids
- Inhibitors
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Heterocycles
