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alinastine

alinastine Struktur
154541-72-7
CAS-Nr.
154541-72-7
Englisch Name:
alinastine
Synonyma:
alinastine;1H-Benzimidazole, 2-[1-[2-[4-(1,1-dimethylethyl)phenyl]ethyl]-4-piperidinyl]-1-(2-ethoxyethyl)-
CBNumber:
CB71332721
Summenformel:
C28H39N3O
Molgewicht:
433.636
MOL-Datei:
154541-72-7.mol

alinastine Eigenschaften

Siedepunkt:
574.2±50.0 °C(Predicted)
Dichte
1.07±0.1 g/cm3(Predicted)
pka
8.78±0.10(Predicted)

Sicherheit

alinastine Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Alinastine ,Fabrica Espanola de Productos Quimicos y Farmaceuticos

Manufacturing Process

1.5 g of a sodium hydride suspension in oil are added to another suspension of 10.83 g of 2-[1-(2-(4-(1,1-dimethylethyl)phenyl)ethyl)piperidin-4-yl]-1Hbenzimidazole in 150 ml of dimethylformamide and the mixture is stirred for 1 h at room temperature, then a solution of 2-(2-ethoxyethyl)tosylate in dimethylformamide are slowly added. The mixture is heated at 60°C for 16 h, poured onto water and extracted with ether. The extracts are washed with water, dried over anhydrous sodium sulfate and concentrated. The obtained oil is purified by column chromatography yielding 6.0 g of 1-(2-ethoxyethyl)-2- [1-(2-(4-(1,1-dimethylethyl)phenyl)ethyl)piperidine-4-yl]-1H-benzimidazole, melting point 138°-140°C.

Therapeutic Function

Antihistaminic, Antiallergic

alinastine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


alinastine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 3)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49734 58
TargetMol Chemicals Inc.
+17819995354
marketing@targetmol.com United States 19956 58
TargetMol Chemicals Inc. 15002134094
marketing@targetmol.cn China 29867 58

  • alinastine
  • 1H-Benzimidazole, 2-[1-[2-[4-(1,1-dimethylethyl)phenyl]ethyl]-4-piperidinyl]-1-(2-ethoxyethyl)-
  • 154541-72-7
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