Z-Leu-Leu-Leu-B(OH)2 (MG262)

179324-22-2

CAS-Nr.: 179324-22-2

Englisch Name:: Z-Leu-Leu-Leu-B(OH)2 (MG262)

Synonyma:: Z-Leu-Leu-Leu-B(OH)2 (MG262);Proteasome Inhibitor III - Calbiochem;L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1R)-1-borono-3-methylbutyl]-;[(1R)-3-methyl-1-[[(2S)-4-methyl-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]pentanoyl]amino]butyl]boronic acid

CBNumber:: CB71562203

Summenformel:: C25H42BN3O6

Molgewicht:: 491.43

MOL-Datei:: 179324-22-2.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 33

Z-Leu-Leu-Leu-B(OH)2 (MG262) Eigenschaften

Dichte: 1.101±0.06 g/cm3(Predicted)

storage temp.: -20C

L?slichkeit: ≥24.57 mg/mL in DMSO; insoluble in H2O; ≥96.4 mg/mL in EtOH

Aggregatzustand: White solid

pka: 9.69±0.43(Predicted)

Farbe: White to off-white

InChIKey: MWKOOGAFELWOCD-FKBYEOEOSA-N

Sicherheit

WGK Germany	WGK 1
Speicherklasse	11 - Combustible Solids

Z-Leu-Leu-Leu-B(OH)2 (MG262) Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

A boronic acid-based, reversible proteasome inhibitor that is structurally similar to MG-132 (Cat. No. 474790) but displays much higher potency (K_i = 0.03 nM versus 4 nM for MG-132).

Biochem/physiol Actions

Target Ki: 30 pM against proteasome

Z-Leu-Leu-Leu-B(OH)2 (MG262) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Z-Leu-Leu-Leu-B(OH)2 (MG262) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 33)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131956	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51395	80
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9804	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58
Zhengzhou Akem Chemical Co., Ltd	13303867194	3001317055@qq.com	China	9996	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24958	58
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9835	58
Adipogen Life Sciences	--	info@adipogen.com	China	5293	58

Z-Leu-Leu-Leu-B(OH)2 (MG262)
[(1R)-3-methyl-1-[[(2S)-4-methyl-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]pentanoyl]amino]butyl]boronic acid
Proteasome Inhibitor III - Calbiochem
L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1R)-1-borono-3-methylbutyl]-
179324-22-2
C25H42BN3O6

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