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Diprophyllin

Diprophylline Struktur
479-18-5
CAS-Nr.
479-18-5
Bezeichnung:
Diprophyllin
Englisch Name:
Diprophylline
Synonyma:
DYPHYLLINE;DIPHYLLIN;Dihydroxypropyl;7-(2,3-DIHYDROXYPROPYL)THEOPHYLLINE;Dilor;Coronarin;dihydroxypropyltheophylline;Teofen;Circain;Neophyl
CBNumber:
CB7177891
Summenformel:
C10H14N4O4
Molgewicht:
254.24
MOL-Datei:
479-18-5.mol

Diprophyllin Eigenschaften

Schmelzpunkt:
161-162 °C(lit.)
Siedepunkt:
397.46°C (rough estimate)
Dichte
1.3036 (rough estimate)
Brechungsindex
1.6200 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
L?slichkeit
Freely soluble in water, slightly soluble in ethanol (96 per cent).
Aggregatzustand
Powder
pka
13.74±0.20(Predicted)
Farbe
White
Wasserl?slichkeit
33 g/100 mL (25 ºC)
Merck 
14,3479
BRN 
284563
Stabilit?t:
Hygroscopic
Kosmetik-Inhaltsstoffe Funktionen
SKIN CONDITIONING
InChI
1S/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3
InChIKey
KSCFJBIXMNOVSH-UHFFFAOYSA-N
SMILES
CN1C(=O)N(C)c2ncn(CC(O)CO)c2C1=O
LogP
-1.100 (est)
CAS Datenbank
479-18-5(CAS DataBase Reference)
NIST chemische Informationen
Dyphylline(479-18-5)
EPA chemische Informationen
Dyphylline (479-18-5)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn,Xi
R-S?tze: 22-36/37/38
S-S?tze: 36-36/37-26
WGK Germany  3
RTECS-Nr. XH5100000
TSCA  TSCA listed
HS Code  29395900
Speicherklasse 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Giftige Stoffe Daten 479-18-5(Hazardous Substances Data)
Toxizit?t LD50 in mice (mg/kg): 3400 orally; 1430 s.c. (Al'tshuler)
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
Sicherheit

Diprophyllin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R22:Gesundheitssch?dlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

Dyphylline is the N-7 dihydroxypropyl derivative of theophylline and is not a theophylline salt. Dyphylline does not get metabolized to theophylline in vivo, and even though it contains 70% theophylline by molecular weight ratio, the equivalent amount to theophylline is not known. Dosing must be accomplished independently by monitoring dyphylline blood levels. Dyphylline has a diminished bronchodilator effect compared to theophylline, but it may have lower and less serious side effects. Dosage forms available are an elixir and tablets.

Chemische Eigenschaften

white to light yellow crystal powder

Verwenden

PDE inhibitor, bronchodilator, vasodilator

Definition

ChEBI: An oxopurine that is theophylline bearing a 2,3-dihydroxypropyl group at the 7 position. It has broncho- and vasodilator properties, and is used in the treatment of asthma, cardiac dyspnea, and bronchitis. It is also an ingredient in preparations that have been promoted for coughs.

Diprophyllin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Diprophyllin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 430)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Suikang Pharmaceutical Co.,Ltd.
+86-18239973690
sales@suikangpharm.com China 311 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055
Sibel@chuanghaibio.com China 8738 58
Hebei Yanxi Chemical Co., Ltd.
+8618531123677
faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615531151365
mina@chuanghaibio.com China 18126 58
shandong perfect biotechnology co.ltd
+86-53169958659 +86-13153181156
sales@sdperfect.com China 294 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649
sarah@tnjone.com China 1143 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29640 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21587 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29815 58
Hebei Jimi Trading Co., Ltd.
+86 319 5273535
bestoneforyou@sina.com CHINA 287 58

479-18-5(Diprophyllin)Verwandte Suche:


  • 7-(2,3-Dihydroxypropyl)-1,3-dimethylxanthine
  • 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-
  • 1h-purine-2,6-dione,7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl
  • 7-(2,3-Dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
  • circair
  • component of Dilor g
  • component of Neothylline-gg
  • Coronal
  • Dihydroxypropyl theophylline
  • Dihydroxypropyl theopylin
  • dihydroxypropyltheopylin
  • Diprofillin
  • Diprofilline
  • diprophyllinee
  • Dipropylline
  • Droxine
  • Dyflex
  • Glyfyllin
  • Glyphyllin
  • Glyphylline
  • Hiphyllin
  • Hyphylline
  • Iphyllin
  • Liactemin
  • neophyllinm
  • neostenorasan
  • Neufil
  • Neutrafillina
  • Neutraphylline
  • Neutroxantina
  • propylphyllin
  • Propyphyllin
  • Protheophylline
  • Purifilin
  • sibephyllin
  • sibephylline
  • Silbephylline
  • Solufilin
  • Solufyllin
  • Soluphyllin
  • Synthophylline
  • Tefilan
  • tesfen
  • Theal
  • thealampules
  • Thefylan
  • Theophylline, 7-(2,3-dihydroxypropyl)-
  • DIPROPHYLLINE (7-(2,3-DIHYDROXYPROPYL)THEOPHYLLINE)
  • Diprophylline ,99%
  • 7-(2,3-Dihydroxypropyl)theophylline,99%
  • 7-(2,3-Dihydroxypropyl)theophyllineDyphylline
  • DIPROPHYLLIN(RG)
  • Dyphylline (200 mg)
  • 7-(2,3-Dihydroxyprop
  • Two hydroxypropyl theophylline
  • Dyphylline(Dilor)
  • Dyphylline, USP
  • Dihydroxypropyl)theophyllin
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