CDK2 INHIBITOR II
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- CAS-Nr.
- 222035-13-4
- Englisch Name:
- CDK2 INHIBITOR II
- Synonyma:
- SC 221409;COMPOUND 3;CDK2 INHIBITOR II;CDK2-IN-3 (compound 3);SC 221409, Cdk2 inhibitor;4-(2-(5-Bromo-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide;4-[2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-benzenesulfonamide;Benzenesulfonamide, 4-[2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-
- CBNumber:
- CB7244623
- Summenformel:
- C14H11BrN4O3S
- Molgewicht:
- 395.23
- MOL-Datei:
- 222035-13-4.mol
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CDK2 INHIBITOR II Eigenschaften
- Schmelzpunkt:
- >272°C (dec.)
- Dichte
- 1.85±0.1 g/cm3(Predicted)
- storage temp.
- Amber Vial, -20°C Freezer, Under inert atmosphere
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly, Heated)
- Aggregatzustand
- Solid
- pka
- 8.81±0.20(Predicted)
- Farbe
- Light Orange to Orange
- InChI
- InChI=1S/C14H11BrN4O3S/c15-8-1-6-12-11(7-8)13(14(20)17-12)19-18-9-2-4-10(5-3-9)23(16,21)22/h1-7,18H,(H2,16,21,22)(H,17,19,20)
- InChIKey
- ODZNNZYRBRRREX-UHFFFAOYSA-N
- SMILES
- C1(S(N)(=O)=O)=CC=C(NN=C2C3=C(NC2=O)C=CC(Br)=C3)C=C1
CDK2 INHIBITOR II Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
The cyclin-
dependent kinase 2 (Cdk2) works with cyclins A or E to regulate S phase and G
2-
M transition during the cell cycle. Cdk2 Inhibitor II is a 3-
(benzylidne)indolin-
2-
one analog that selectively and potently inhibits Cdk2 (IC
50 = 60 nM). It is cell permeable, reversible, and ATP-
competitive.
Verwenden
CDK2 inhibitor II, is a potent, cell-permeable, ATP-competitive, and selective inhibitor of Cdk2.
CDK2 INHIBITOR II Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
CDK2 INHIBITOR II Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 40)Lieferanten
- COMPOUND 3
- CDK2 INHIBITOR II
- SC 221409
- Benzenesulfonamide, 4-[2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-
- CDK2-IN-3 (compound 3)
- 4-(2-(5-Bromo-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide
- 4-[2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-benzenesulfonamide
- SC 221409, Cdk2 inhibitor
- 222035-13-4
- Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
