N-[(1S,3S)-1-[(ETHOXYMETHOXY)METHYL]-4-(HYDROXYAMINO)-3-METHYL-4-OXOBUTYL]-4-PHENOXYBENZAMIDE

223472-31-9

CAS-Nr.: 223472-31-9

Englisch Name:: N-[(1S,3S)-1-[(ETHOXYMETHOXY)METHYL]-4-(HYDROXYAMINO)-3-METHYL-4-OXOBUTYL]-4-PHENOXYBENZAMIDE

Synonyma:: ONO 4817;MMP Inhibitor V;N-[(1S,3S)-1-[(ETHOXYMETHOXY)METHYL]-4-(HYDROXYAMINO)-3-METHYL-4-OXOBUTYL]-4-PHENOXYBENZAMIDE;Benzamide, N-[(1S,3S)-1-[(ethoxymethoxy)methyl]-4-(hydroxyamino)-3-methyl-4-oxobutyl]-4-phenoxy-

CBNumber:: CB72453430

Summenformel:: C22H28N2O6

Molgewicht:: 416.47

MOL-Datei:: 223472-31-9.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 41

N-[(1S,3S)-1-[(ETHOXYMETHOXY)METHYL]-4-(HYDROXYAMINO)-3-METHYL-4-OXOBUTYL]-4-PHENOXYBENZAMIDE Eigenschaften

Dichte: 1.192±0.06 g/cm3(Predicted)

storage temp.: Store at RT

L?slichkeit: <20.82mg/ml in ethanol; <41.65mg/ml in DMSO

Aggregatzustand: solid

pka: 9.55±0.40(Predicted)

Farbe: Off-white

InChIKey: HDWWQELUBWGQGA-WMZOPIPTSA-N

SMILES: N(O)C(=O)[C@H](C[C@H](NC(=O)c1ccc(cc1)Oc2ccccc2)COCOCC)C

Sicherheit

WGK Germany	WGK 1
Speicherklasse	11 - Combustible Solids

N-[(1S,3S)-1-[(ETHOXYMETHOXY)METHYL]-4-(HYDROXYAMINO)-3-METHYL-4-OXOBUTYL]-4-PHENOXYBENZAMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

MMP Inhibitor V is a broad-spectrum inhibitor of matrix metalloproteinase (MMPs).

Biologische Aktivit?t

Broad spectrum MMP inhibitor; K i values are 0.45, 0.73, 1.1, 1.1, 2.1, 42 and 2500 nM for MMP-12, MMP-2, MMP-8, MMP-13, MMP-9, MMP-3 and MMP-7 respectively and IC 50 = 1600 nM for MMP-1). Displays no activity at other proteases up to a concentration of 100 μ M. Exhibits antiangiogenic and anti-invasive properties on lung metastasis of murine renal cell carcinoma.

N-[(1S,3S)-1-[(ETHOXYMETHOXY)METHYL]-4-(HYDROXYAMINO)-3-METHYL-4-OXOBUTYL]-4-PHENOXYBENZAMIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-[(1S,3S)-1-[(ETHOXYMETHOXY)METHYL]-4-(HYDROXYAMINO)-3-METHYL-4-OXOBUTYL]-4-PHENOXYBENZAMIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 41)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32468	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9804	58
Alabiotech Inc.	001-619-354-5251	sales@alabiotech-e.com	United States	972	60
Alpha Biopharmaceuticals Co., Ltd	0411-39042497	sales@alphabiopharm.com	China	1951	58

N-[(1S,3S)-1-[(ETHOXYMETHOXY)METHYL]-4-(HYDROXYAMINO)-3-METHYL-4-OXOBUTYL]-4-PHENOXYBENZAMIDE
ONO 4817
MMP Inhibitor V
Benzamide, N-[(1S,3S)-1-[(ethoxymethoxy)methyl]-4-(hydroxyamino)-3-methyl-4-oxobutyl]-4-phenoxy-
223472-31-9

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