Begacestat

769169-27-9

CAS-Nr.: 769169-27-9

Englisch Name:: Begacestat

Synonyma:: GSI-953;Begacestat;Begacestat(GSI-953);GSI-953 DISCONTINUED;Begacestat (Synonyms: GSI-953);5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxyMethyl)-2-(trifluoroMethyl)propyl]-2-thiophenesulfonaMide;2-Thiophenesulfonamide, 5-chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2-(trifluoromethyl)propyl]-;5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2- (trifluoromethyl)propyl] thiophene-2-sulfonamide;(2S)-S-(5-chlorothiophen-2-yl)-4,4,4-trifluoro-1-hydroxy-N-Methyl-3-(trifluoroMethyl)butane-2-sulfonaMido

CBNumber:: CB72535664

Summenformel:: C9H8ClF6NO3S2

Molgewicht:: 391.74

MOL-Datei:: 769169-27-9.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 69

Begacestat Eigenschaften

Schmelzpunkt:: 153-155°C

Siedepunkt:: 355℃

Dichte: 1.642

Flammpunkt:: 169℃

storage temp.: 2-8°C

L?slichkeit: DMSO: ≥15mg/mL

Aggregatzustand: powder

pka: 8.16±0.50(Predicted)

Farbe: white to tan

InChI: 1S/C9H8ClF6NO3S2/c10-5-1-2-6(21-5)22(19,20)17-4(3-18)7(8(11,12)13)9(14,15)16/h1-2,4,7,17-18H,3H2/t4-/m1/s1

InChIKey: PSXOKXJMVRSARX-SCSAIBSYSA-N

SMILES: OC[C@@H](NS(=O)(=O)c1ccc(Cl)s1)C(C(F)(F)F)C(F)(F)F

Sicherheit

WGK Germany	3
Speicherklasse	11 - Combustible Solids

Begacestat Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Begacestat (GSI-953) is a selective β-secretase inhibitor that selectively inhibits cleavage of APP over Notch. GSI-953 is used for treating diseases such as cancer in relation to prevention of intestinal secretory metaplasia.

Begacestat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Begacestat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 69)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39040	58
J & K SCIENTIFIC LTD.	18210857532; 18210857532	jkinfo@jkchemical.com	China	96815	76
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15402	60
shanghai cooperpharm co.,LTD .	+86-021-58975553	sales@cooperpharm.com	China	1210	56
Quality Control Solutions Ltd.	0755-66853366 13670046396	orders@qcsrm.com	China	18190	56
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9804	58
Shanghai BetterBioChem Co., Ltd.	+86-18017644823	sales@betterbiochem.com	China	325	58

Begacestat
Begacestat(GSI-953)
GSI-953
5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxyMethyl)-2-(trifluoroMethyl)propyl]-2-thiophenesulfonaMide
(2S)-S-(5-chlorothiophen-2-yl)-4,4,4-trifluoro-1-hydroxy-N-Methyl-3-(trifluoroMethyl)butane-2-sulfonaMido
5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2- (trifluoromethyl)propyl] thiophene-2-sulfonamide
2-Thiophenesulfonamide, 5-chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2-(trifluoromethyl)propyl]-
Begacestat (Synonyms: GSI-953)
GSI-953 DISCONTINUED
769169-27-9
C9H8ClF6NO3S2
Heterocycles
Inhibitors
Intermediates & Fine Chemicals
Pfizer Compounds
Pharmaceuticals
Sulfur & Selenium Compounds

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