GW 803430
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- CAS-Nr.
- 515141-51-2
- Englisch Name:
- GW 803430
- Synonyma:
- GW 3430;GW 803430;GW-803430A;GW 803430,GW803430;GW-803430 >=98% (HPLC);Thieno[3,2-d]pyrimidin-4(3H)-one, 6-(4-chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy];6-(4-Chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-thieno[3,2-d]pyrimidin-4(3H)-one;6-(4-chloro-phenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-3H-thieno[3,2-d]pyrimidin-4-one;Thieno[3,2-d]pyrimidin-4(3H)-one, 6-(4-chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-
- CBNumber:
- CB72538276
- Summenformel:
- C25H24ClN3O3S
- Molgewicht:
- 481.99
- MOL-Datei:
- 515141-51-2.mol
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GW 803430 Eigenschaften
- Siedepunkt:
- 677.7±65.0 °C(Predicted)
- Dichte
- 1.37±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: ≥4mg/mL at warmed to 60°C
- Aggregatzustand
- powder
- pka
- 9.52±0.20(Predicted)
- Farbe
- white to beige
- InChI
- 1S/C25H24ClN3O3S/c1-31-22-14-19(8-9-21(22)32-13-12-28-10-2-3-11-28)29-16-27-20-15-23(33-24(20)25(29)30)17-4-6-18(26)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3
- InChIKey
- MWULMTACIBZPGN-UHFFFAOYSA-N
- SMILES
- [s]1c2c(nc[n]([c]2=O)c4cc(c(cc4)OCCN5CCCC5)OC)cc1c3ccc(cc3)Cl
GW 803430 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
GW 803430 is a melanin-concentrating hormone receptor 1( MCH1) antagonist for treatment of obesity and depression.
Biochem/physiol Actions
GW-803430 antagonizes central MCHR1 and produces anxiolytic, anti-depressant and anti-obesity effects in rats and mice. It also controls the alcohol-seeking behavior in rats and is a promising treatment for alcohol use-related disorders.
GW 803430 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
GW 803430 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 45)Lieferanten
- Thieno[3,2-d]pyrimidin-4(3H)-one, 6-(4-chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]
- GW 803430
- GW 3430
- 6-(4-chloro-phenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-3H-thieno[3,2-d]pyrimidin-4-one
- GW-803430A
- Thieno[3,2-d]pyrimidin-4(3H)-one, 6-(4-chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-
- 6-(4-Chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-thieno[3,2-d]pyrimidin-4(3H)-one
- GW-803430 >=98% (HPLC)
- GW 803430,GW803430
- 515141-51-2
