Edoxaban tosylate
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- CAS-Nr.
- 480449-71-6
- Englisch Name:
- Edoxaban tosylate
- Synonyma:
- DU-176b;Edoxaban TsOH;Edoxaban tosylate;Edoxaban (TsOH salt);Edoxaban p-Toluenesulfonate;Edoxaban tosylate
(DU-176b);9H-FLUORENE-2,11-DICARBOXYLICACID;C24H30ClN7O4S.C7H7HSO3 Edoxaban (TsOH salt) 480449-71-6;N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide;N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide 4-methylbenzenesulfonate
- CBNumber:
- CB72627790
- Summenformel:
- C24H30ClN7O4S.C7H8O3S
- Molgewicht:
- 720.26
- MOL-Datei:
- 480449-71-6.mol
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Edoxaban tosylate Eigenschaften
- storage temp.
- Store at -20°C
- L?slichkeit
- 25℃: DMSO
- Aggregatzustand
- Powder
- Farbe
- White to off-white
- InChIKey
- ZLFZITWZOYXXAW-BUZWFPPCNA-N
- SMILES
- S(C1C=CC(C)=CC=1)(O)(=O)=O.N([C@@H]1C[C@@H](C(=O)N(C)C)CC[C@@H]1NC(=O)C(=O)NC1N=CC(Cl)=CC=1)C(C1SC2CN(C)CCC=2N=1)=O |&1:12,14,22,r|
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
WGK 3 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P330 |
Mund ausspülen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Edoxaban tosylate Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Edoxaban tosylate (Lixiana; Daiichi Sankyo, Tokyo, Japan), known as DU-176b in clinical trials, is a novel oral direct factor Xa inhibitor. Edoxaban has good bioavailability with maximum plasma concentration achieved 1–2 h after ingestion and plasma half-life of 8–10 h. Edoxaban is a novel anticoagulant (NOAC) indicated to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis and pulmonary embolism.
Definition
ChEBI: An organosulfonate salt obtained by combining equimolar amounts of edoxaban and 4-toluenesulfonic acid. Used (in the form of its monohydrate) for the treatment of deep vein thrombosis and pulmonary embolism.
Edoxaban tosylate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Edoxaban tosylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 152)Lieferanten
- Edoxaban TsOH
- Edoxaban (TsOH salt)
- Edoxaban tosylate
- Edoxaban tosylate
(DU-176b)
- C24H30ClN7O4S.C7H7HSO3 Edoxaban (TsOH salt) 480449-71-6
- 9H-FLUORENE-2,11-DICARBOXYLICACID
- Edoxaban p-Toluenesulfonate
- N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide
- N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide 4-methylbenzenesulfonate
- N-(5-Chloropyridin-2-yl)-N′-((1S,2R,4S)-4-[(dimethyl amino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl)ethanediamide p-toluenesulfonate
- Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate (1:1)
- DU-176b
- 480449-71-6
- 480448-71-6
- 824193-20-8
- C24H30ClN7O4SC7H7HSO3
- C31H38ClN7O7S2
- C24H30ClN7O4SC7H8O3S
