Madecassic acid
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- CAS-Nr.
- 18449-41-7
- Englisch Name:
- Madecassic acid
- Synonyma:
- Madecasoside;MADECASSIC ACID;MADECASSIC ACID(P);Madecassic acid-RM;Hydroxyasiatic acid;Hydroxy asiaticoside;6-Hydroxyasiatic acid;Madecassic Acid (97%);Brahmic acid 18449-41-7;6BETA-HYDROXYASIATIC ACID
- CBNumber:
- CB7280283
- Summenformel:
- C30H48O6
- Molgewicht:
- 504.71
- MOL-Datei:
- 18449-41-7.mol
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Madecassic acid Eigenschaften
- Schmelzpunkt:
- 270°C (dec.)
- Siedepunkt:
- 641.7±55.0 °C(Predicted)
- Dichte
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO (Sparingly), Methanol (Slightly, Heated)
- pka
- 4.63±0.70(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Pale Red
- Major Application
- food and beverages
- Kosmetik-Inhaltsstoffe Funktionen
- SKIN CONDITIONING
- InChIKey
- PRAUVHZJPXOEIF-MRQYELSVNA-N
- SMILES
- O[C@H]1[C@@H]2[C@@]([C@@H]3[C@]([C@@]4(CC[C@@]5([C@@H]([C@H]([C@@H](CC5)C)C)C4=CC3)C(=O)O)C)(C1)C)(C[C@H]([C@@H]([C@]2(CO)C)O)O)C
- LogP
- 4.321 (est)
Madecassic acid Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Madecassic acid is a triterpenoid that has been found in
C. asiatica and has diverse biological activities. It inhibits LPS-induced production of nitric oxide (NO), prostaglandin E
2 (PGE
2; ), TNF-α, IL-1β, and IL-6 in RAW 264.7 macrophages when used at a concentration of 150 μg/ml. Madecassic acid (0.05 and 0.1% in the diet) decreases plasma levels of fibrinogenin and triglycerides, as well as heart and kidney levels of reactive oxygen species (ROS), in a mouse model of diabetes induced by streptozotocin (STZ; ). It decreases tumor growth in a CT26 murine colon cancer model in a dose-dependent manner.
Chemische Eigenschaften
White powder
Definition
ChEBI: A pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3, 6 and 23 (the 2alpha,3beta,6beta stereoisomer).
Madecassic acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Madecassic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 396)Lieferanten
18449-41-7()Verwandte Suche:
- (2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oic acid
- MADECASSIC ACID
- Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2.alpha.,3.beta.,4.alpha.,6.beta.)-
- (1S,2R,4aS,6aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bR)-8,10,11-trihydroxy -9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,1 1,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
- Hydroxy asiaticoside
- MADECASSIC ACID(P)
- 6BETA-HYDROXYASIATIC ACID
- 2α,3β,6β,23-Tetrahydroxyurs-12-en-28-oic acid
- 6-Hydroxyasiatic acid
- Madecassic acid, froM Centella asiatica
- (1S,2R,4aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,12bR,14bS)-8,10,11-Trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
- (1S,2R,4aS,6aS,6bR,8R,9R,10R,11R,12aR)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
- Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,4α,6β)-
- Madecassic Acid (97%)
- Brahmic acid 18449-41-7
- Urs-12-en-28-oic acid,2,3,6,23-tetrahydroxy-, (2a,3b,4a,6b)-
- Madecassic acid, 98%, from Centella asiatica (L.) Urb.
- Hydroxycentella glycoside
- Madecassic acid/Madecassoide
- Hydroxyasiatic acid
- Madecassic acid-RM
- Madecassic acid, 10 mM in DMSO
- Madecassic acid (Standard)
- Madecasoside
- 18449-41-7
- C30H48O6
- Inhibitors
- Cofactor
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Miscellaneous Natural Products
- The group of Asiaticoside
