1-Bromodibenzothiophene
|
|
|
- CAS-Nr.
- 65642-94-6
- Englisch Name:
- 1-Bromodibenzothiophene
- Synonyma:
- 1-bromodibenzo[b,d]thiophene;1-Bromodibenzothiophene;Dibenzothiophene, 1-bromo-;1-bromodibenzenebenzothiophene;1-Bromodibenzothiophene ISO 9001：2015 REACH
- CBNumber:
- CB73051910
- Summenformel:
- C12H7BrS
- Molgewicht:
- 263.15
- MOL-Datei:
- 65642-94-6.mol
|
1-Bromodibenzothiophene Eigenschaften
- Schmelzpunkt:
- 84 °C
- Siedepunkt:
- 386.6±15.0 °C(Predicted)
- Dichte
- 1.611±0.06 g/cm3(Predicted)
- storage temp.
- Store at room temperature
- Aggregatzustand
- powder to crystal
- Farbe
- White to Orange to Green
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Achtung
|
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H227 |
Combustible liquid |
Flammable liquids |
Category 4 |
Warnung |
|
P210, P280, P370+P378, P403+P235,P501 |
| H314 |
Verursacht schwere Ver?tzungen der Haut und schwere Augensch?den. |
?tzwirkung auf die Haut |
Kategorie 1B |
Achtung |
|
P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501 |
|
| Sicherheit |
| P210 |
Von Hitze, hei?en Oberfl?chen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P301+P330+P331 |
BEI VERSCHLUCKEN: Mund ausspülen. KEIN Erbrechen herbeiführen. |
| P303+P361+P353 |
BEI BERüHRUNG MIT DER HAUT (oder dem Haar): Alle kontaminierten Kleidungsstücke sofort ausziehen. Haut mit Wasser abwaschen oder duschen. |
| P304+P340 |
BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
| P310 |
Sofort GIFTINFORMATIONSZENTRUM/Arzt/ anrufen. |
| P363 |
Kontaminierte Kleidung vor erneutem Tragen waschen. |
| P370+P378 |
Bei Brand: zum L?schen verwenden. |
|
1-Bromodibenzothiophene Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
1-Bromodibenzothiophene can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
Synthese
Into a 1 L four-necked round bottom flask equipped with a stirrer, a Liebig condenser (not required), a 100 mL dropping funnel and a thermometer, 43.5 g (0.156 mol) of the amine hydrochloride obtained in the above ), 240 mL of acetic acid, 55 mL of concentrated hydrochloric acid and 143 mL of water were placed and cooled to -5 C. or lower in an ice water bath. Next, an aqueous solution of 12.0 g (0.173 mol) of sodium nitrite dissolved in 67 mL of water was added dropwise from the dropping funnel at a temperature not exceeding 5 C., and the mixture was stirred at 5 C. or less for 1 hour.The resulting diazo solution was transferred to a 1 L dropping funnel and set in a 1 L 4-necked round bottom flask equipped with a stirrer, a Liebig condenser (not required) and a thermometer, and then 50 % Hypophosphorous acid and 90 mL of water were added, and the mixture was cooled to -5 C. or lower in an ice water bath. Subsequently, the diazo solution was added dropwise at a temperature not exceeding 5 C., after stirring for 1 hour in an ice water bath, it was returned to room temperature and stirred at room temperature for 48 hours.The obtained reaction solution was extracted twice with 310 mL of ethyl acetate, then washed twice with 310 mL of water, dried with magnesium sulfate, magnesium sulfate was removed by suction filtration, and the solvent was distilled off under reduced pressure. Subsequently, the obtained crude oil was purified on a silica gel column using n-heptane as a developing solution to obtain 33.8 g (yield: 82.5%) of the desired bromide.
1-Bromodibenzothiophene Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1-Bromodibenzothiophene Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 110)Lieferanten
- 1-Bromodibenzothiophene
- Dibenzothiophene, 1-bromo-
- 1-Bromodibenzothiophene ISO 9001：2015 REACH
- 1-bromodibenzenebenzothiophene
- 1-bromodibenzo[b,d]thiophene
- 65642-94-6
- oled
