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(Z)-Guggulsterone

(Z)-Guggulsterone Struktur
95975-55-6
CAS-Nr.
95975-55-6
Englisch Name:
(Z)-Guggulsterone
Synonyma:
GUGGULSTERONE;NSC 37445;Stersterone;GUGULSTERONE;GUGGULSTERONE Z;GUGGULESTERONES;GUGGULESTERONE Z;Coumarin sterone;CIS GUGGULSTERONE;Guggulsterone E&Z
CBNumber:
CB7309069
Summenformel:
C21H28O2
Molgewicht:
312.45
MOL-Datei:
95975-55-6.mol

(Z)-Guggulsterone Eigenschaften

Siedepunkt:
463.3±45.0 °C(Predicted)
Dichte
1.10±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
DMSO: 5 mg/mL
Aggregatzustand
powder
Farbe
light yellow
InChI
InChI=1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/t15-,17+,18+,20+,21-/m1/s1
InChIKey
WDXRGPWQVHZTQJ-NRJJLHBYSA-N
SMILES
C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)C(=CC)C(=O)C3)CC2
CAS Datenbank
95975-55-6(CAS DataBase Reference)

Sicherheit

Kennzeichnung gef?hrlicher Xi
R-S?tze: 37
S-S?tze: 36
WGK Germany  3
HS Code  29147000

(Z)-Guggulsterone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R37:Reizt die Atmungsorgane.

S-S?tze Betriebsanweisung:

S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Verwenden

Guggulsterone is a broad spectrum steroid receptor ligand. Gum resin of Commiphora mukul marketed as an antihyperlipidemic drug.

Biologische Aktivit?t

Broad spectrum steroid receptor ligand; binds with high affinity to mineralocorticoid receptors (K i = 39 nM) and lower affinity to progesterone, androgen and glucocorticoid receptors (K i values are 201, 240 and 224 nM respectively). Functions primarily as an antagonist of these receptors, with the exception of the progesterone receptor where it displays partial agonist effects. Also exerts hypolipidemic activity, likely via antagonism of the receptor for bile acids (farnesoid X receptor; FXR).

(Z)-Guggulsterone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


(Z)-Guggulsterone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 210)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Dingwang Technology (Wuhan) Co., Ltd.
+undefined-27-2786652399 +undefined13627115097
market02@senwayer.com China 887 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29812 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897
sales@biopurify.com China 4616 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780
sale@simagchem.com China 17346 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32467 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 28509 58
AFINE CHEMICALS LIMITED
+86-571-85134551
info@afinechem.com China 15083 58
Finetech Industry Limited
+86-27-8746-5837 +8619945049750
info@finetechnology-ind.com China 9539 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739
info@dycnchem.com China 52704 58

95975-55-6()Verwandte Suche:


  • 4,17(20)-(CIS)-PREGNADIEN-3,16-DIONE
  • PREGNA-4,17(20)-DIENE-3,16-DIONE
  • (8S,9R,10R,13S,14S,17E)-17-(1-methoxyethylidene)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione
  • pregna-4,17-diene-3,16-dione
  • GUGGULISTERONES 95%
  • CIS-4,17(20)-PREGNADIENE-3,16-DIONE
  • CIS GUGGULSTERONE
  • GUGULSTERONE
  • GUGGULSTERONE Z
  • GUGGULSTERONE (Z FORM)
  • GUGGULESTERONE Z
  • (17Z)-Pregna-4,17(20)-diene-3,16-dione
  • (17E)-Pregna-4,17(20)-diene-3,16-dione
  • GUGGULSTERONES E&Z(MIX)(FG)
  • GuggulsteronesE&Z(mix)
  • (E&Z)-Guggulsterone
  • Guggulsterone E&Z
  • Guggulsterones E&Z
  • (Z)-Guggulsterone
  • Guggulsterone E and Z
  • Stersterone
  • (Z)-Guggulsterone/Guggulsterone
  • GUGGULESTERONES
  • GUGGULSTERONE (GUGG),CAS:95975-55-6
  • NSC 37445
  • GUGGULSTERONE
  • Coumarin sterone
  • Guggulsterone(pregna-4,17-diene-3,16-dione)
  • (8R,9S,10R,13S,14S)-17-Ethylidene-10,13-dimethyl-7,8,9,10,11,12,13,14,15,17-decahydro-1H-cyclopenta[a]phenanthrene-3,16(2H,6H)-dione
  • Guggulsterone (pregna-4,17-diene-3,16-dione), steroid receptor antagonist
  • Guggulsterone, 10 mM in DMSO
  • Xiangjiao steroid ketone/solid steroid ketone (mixture of E and Z)
  • 95975-55-6
  • Alphabetic
  • Analytical Chromatography Product Catalog
  • Analytical Standards
  • Miscellaneous
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