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ANTI-DEVELOPMENTALLY-REGULATED BRAIN PROTEIN

ANTI-DEVELOPMENTALLY-REGULATED BRAIN PROTEIN Struktur
CAS-Nr.
Englisch Name:
ANTI-DEVELOPMENTALLY-REGULATED BRAIN PROTEIN
Synonyma:
ANTI-DREBRIN;ANTI-DREBRIN, HUMAN;ANTI-DEVELOPMENTALLY-REGULATED BRAIN PROTEIN;Anti-Drebrin antibody produced in rabbit
CBNumber:
CB7334548
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-DEVELOPMENTALLY-REGULATED BRAIN PROTEIN Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous solution
Biologische Quelle
rabbit

Sicherheit

Kennzeichnung gef?hrlicher Xn
R-S?tze: 21/22
S-S?tze: 36/37
WGK Germany  -
Speicherklasse 12 - Non Combustible Liquids

ANTI-DEVELOPMENTALLY-REGULATED BRAIN PROTEIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

Drebrin is a member of the newly identified ADF-H family of actin-binding proteins that share the structurally conserved actin-depolymerizing factor (ADF) binding module. It is composed of a single ADF-H domain at its N-terminus, followed by a non-conserved central region and a C-terminal SH3 domain. Three isoforms, E1 and E2 (embryonic) and A (adult), have been identified in the brain. An additional truncated form of drebrin A, s-drebrin/A2, is specifically expressed in the adult brain, but not in non-neuronal tissues. Drebrin is also widely expressed in a variety of cells including epithelial, endothelial, and smooth muscle cells and is associated at cell-cell adhering junction sites.

Biochem/physiol Actions

Drebrin (developmentally-regulated brain protein) is a major neuronal F-actin binding protein involved in the control of actin dynamics and neuronal morphogenesis. It colocalizes with actin filaments and dendritic-like cell processes and may be involved in actin remodeling. It binds to and dissociates F-actin stabilizing proteins such as α-actinin, fascin, and tropomyosin from actin filaments. It plays an important role in the formation of axons and dendrites during neuronal development and in neuronal plasticity in the adult brain.

ANTI-DEVELOPMENTALLY-REGULATED BRAIN PROTEIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-DEVELOPMENTALLY-REGULATED BRAIN PROTEIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 16)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51395 80
Shanghai guandao biology engineering co., ltd 18818239863 18818239863;
3171921642@qq.com China 9260 58
Merck KGaA --
ordercn@merckgroup.com China 6394 58
Aoki Biotechnology (Shenzhen) Co., Ltd. --
CHINA 6056 58

  • Anti-Drebrin antibody produced in rabbit
  • ANTI-DREBRIN
  • ANTI-DREBRIN, HUMAN
  • ANTI-DEVELOPMENTALLY-REGULATED BRAIN PROTEIN
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