1-(Triphenylphosphoranyliden)aceton
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- CAS-Nr.
- 1439-36-7
- Bezeichnung:
- 1-(Triphenylphosphoranyliden)aceton
- Englisch Name:
- (ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE
- Synonyma:
- 1-(TRIPHENYLPHOSPHORANYLIDENE)-2-PROPANONE;1-(Triphenylphosphoranylidene)propan-2-one;triphenylphosphoranylidene-2-propanon;(2-Oxopropylidene)triphenylphosphorane;NSC 407394;1-(TriphenyL;phosphoranyL;AURORA KA-1177;idene)-2-propanone;Triphenyl(acetylMethylene)phospho
- CBNumber:
- CB7371857
- Summenformel:
- C21H19OP
- Molgewicht:
- 318.35
- MOL-Datei:
- 1439-36-7.mol
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1-(Triphenylphosphoranyliden)aceton Eigenschaften
- Schmelzpunkt:
- 203-205 °C (lit.)
- Siedepunkt:
- 478.5±28.0 °C(Predicted)
- Dichte
- 1.14
- storage temp.
- Inert atmosphere,Room Temperature
- L?slichkeit
- Soluble in chloroform. Slightly soluble in methanol.
- Aggregatzustand
- Powder
- Farbe
- White to off-white
- Sensitive
- Air Sensitive
- BRN
- 750077
- Stabilit?t:
- Stable. Combustible. Incompatible with strong oxidizing agents.
- InChI
- InChI=1S/C21H19OP/c1-18(22)17-23(19-11-5-2-6-12-19,20-13-7-3-8-14-20)21-15-9-4-10-16-21/h2-17H,1H3
- InChIKey
- KAANTNXREIRLCT-UHFFFAOYSA-N
- SMILES
- C(=P(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)C(=O)C
- CAS Datenbank
- 1439-36-7(CAS DataBase Reference)
1-(Triphenylphosphoranyliden)aceton Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white to light beige crystalline powder
Verwenden
(Acetylmethylene)triphenylphosphorane is used as a Wittig reagent in synthetic chemistry, especially for the synthesis of functionalized pyrrolidines and cyclobutanones. It plays as a vital role in asymmetric allylboration for enantioselective synthesis of (+)-awajanomycin.It is also employed as a reactant in the preparation of 1,2-dioxanes with antitrypanosomal activity. Further, it is used in the preparation of amphibian pyrrolizidine alkaloids through allylic aminations and silicon-containing acyclic dienone musk odorants. In addition to this, it is involved in Domino Suzuki/Heck coupling reactions to prepare fluorenylidenes.
Synthese
The preparative method of (Acetylmethylene)triphenylphosphorane: treatment of Triphenylphosphine with chloro- or Bromoacetone provides the phosphonium salt (eq 1). Deprotonation with a weak base such as bicarbonate in cold water provides the crude ylide which may by isolated by filtration.
1-(Triphenylphosphoranyliden)aceton Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1-(Triphenylphosphoranyliden)aceton Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 245)Lieferanten
1439-36-7(1-(Triphenylphosphoranyliden)aceton)Verwandte Suche:
- (METHYLCARBONYLMETHYLENE)TRIPHENYLPHOSPHORANE
- (ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE
- 1-TRIPHENYLPHOSPHANYLIDENE-PROPAN-2-ONE
- AURORA KA-1177
- triphenylphosphoranylidene-2-propanone
- 1-(triphenylphosphoranylidene)acetone
- 2-Propanone, 1-(triphenylphosphoranylidene)-
- (Acetylylmethylene)triphenylphosphorane, 99 %
- 2-Propanone, triphenylphosphoranylidene.
- Triphenyl(2-oxopropylidene)phosphorane
- 1-Triphenylphosphoranylidene-2-propanone,99%
- (Acetonylidene)triphenylphosphorane
- Methyl (Triphenylphosphoranylidene)Methyl Ketone
- NSC 407394
- Triphenyl(acetylMethylene)phospho
- ACETYLMETHYLENETRIPHENYLPHOSPHORANE FOR
- (Acetylmethylene)triphenylphosphorane, 1-(Triphenylphosphoranylidene)propan-2-one
- (Triphenylphosphoranylidene)acetone
- (Acetylylmethylene)triphenylphosphorane
- 1-Triphenylphosphoranylidene-2-propanone, 99% 25GR
- Acetyl Methylene triphenylphosphine
- 1-Triphenylphosphoranylidine-2-propanone
- 1-(Triphenylphosphoranylidene)-2-propanone 99%
- Acetylmethylenetriphenylphosphorane for synthesis
- (Triphenylphosphoranylidene)acetone 98%
- 1-(TriphenyL
- idene)-2-propanone
- phosphoranyL
- (Acetylmethylene)triphenylphosphorane >
- 1-Triphenylphosphoranylidene-2-propanone, 98%, for synthesis
- 1-(Triphenylphosphoranyliden)aceton
- (2-Oxopropylidene)triphenylphosphorane
- 1-(Triphenylphosphoranylidene)propan-2-one
- 1-(TRIPHENYLPHOSPHORANYLIDENE)-2-PROPANONE
- triphenylphosphoranylidene-2-propanon
- 1439-36-7
- C21H19OP
- C21H19PO
- CH3COCHPC6H53
- Synthetic Reagents
- Wittig Reagents
- C-C Bond Formation
- Wittig & Horner-Emmons Reaction
- Wittig Reaction
- Olefination
- Wittig Reagents
- Synthetic Organic Chemistry
- Wittig & Horner-Emmons Reaction
- Wittig Reaction
