ISOGUVACINE HYDROCHLORIDE
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- CAS-Nr.
- 64603-90-3
- Englisch Name:
- ISOGUVACINE HYDROCHLORIDE
- Synonyma:
- isoguvacine;1,2,3,6-TETRAHYDRO-4-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE;C13694;ISOGUVACINE HCL;Isoguvacine hydrochl;Iloperidone Impurity 66;ISOGUVACINE HYDROCHLORIDE;1,2,3,6-tetrahydro-4-Pyridinecarboxylic acid;ISOGUVACINE HYDROCHLORIDE ISO 9001：2015 REACH;4-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-
- CBNumber:
- CB7406481
- Summenformel:
- C6H9NO2
- Molgewicht:
- 127.14
- MOL-Datei:
- 64603-90-3.mol
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ISOGUVACINE HYDROCHLORIDE Eigenschaften
- Schmelzpunkt:
- 220 °C
- Siedepunkt:
- 280.8±35.0 °C(Predicted)
- Dichte
- 1.199±0.06 g/cm3(Predicted)
- RTECS-Nr.
- US5908286
- storage temp.
- Store at RT
- L?slichkeit
- H2O: refrigerate if not used immediately.soluble
- Aggregatzustand
- solid
- pka
- pK1:9.07 (25°C)
- Farbe
- white
- Wasserl?slichkeit
- Soluble in water
ISOGUVACINE HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
This base is isolated, together with Guvacine (q.v.) from the nuts of Areca
catechu. It is optically inactive and yields crystalline salts: the hydrochloride,
m.p. 231°C; aurich1oride, m.p. 198- 200°C and the p1atinich1oride, m.p. 235°C.
The alkaloid is faintly acid to litmus and on methylation gives the N-methyl
derivative which, on more vigorous methylation yields the dimethyl compound
giving a crystalline platinichloride, m.p. 252°C. The above melting points suggest
that the base may be mainly Arecaidine (q.v.) but on distillation with Zn dust,
it yields products with the characteristic pyrrole reaction.
Chemische Eigenschaften
bp 195-197°C
Biologische Aktivit?t
Specific GABA A receptor agonist.
Einzelnachweise
Jahns., Ber., 21,3404 (1888)
Jahns., ibid, 23, 2972 (1890)
Jahns., ibid, 24,2615 (1891)
Jahns., Arch. Pharrn., 229, 669 (1891)
Trier., Zeit. Physiol. Chern., 85,372 (1913)
ISOGUVACINE HYDROCHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ISOGUVACINE HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 56)Lieferanten
- C13694
- 1,2,3,6-tetrahydro-4-Pyridinecarboxylic acid
- 4-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-
- ISOGUVACINE HCL
- ISOGUVACINE HYDROCHLORIDE
- 1,2,3,6-TETRAHYDRO-PYRIDINE-4-CARBOXYLIC ACIDHYDROCHLORIDE
- Isoguvacine hydrochl
- ISOGUVACINE HYDROCHLORIDE ISO 9001：2015 REACH
- 1,2,3,6-Tetrahydropyridine-4-carboxylic Acid (Isoguvacine)
- 1,2,3,6-TETRAHYDRO-4-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE
- isoguvacine
- Iloperidone Impurity 66
- 64603-90-3
- Cell Biology
- Cell Signaling and Neuroscience
- BioChemical
- Ion Channels
- Ligand-Gated Ion Channels
- GABA and Glycine Receptor Modulators
- GABA/Glycine receptor
