RAC 8-HYDROXY EFAVIRENZ

205754-33-2

CAS-Nr.: 205754-33-2

Englisch Name:: RAC 8-HYDROXY EFAVIRENZ

Synonyma:: 8-HydroxyEfavirenz;RAC 8-HYDROXY EFAVIRENZ;8-hydroxy Efavirenz (Standard);8-Hydroxyefavirenz/205754-33-2;Efavirenz Impurity 11(8-Hydroxy Efavirenz);(4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one;6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one;2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-;(S)-6-Chloro-4-(cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one;2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-

CBNumber:: CB7501021

Summenformel:: C14H9ClF3NO3

Molgewicht:: 331.67

MOL-Datei:: 205754-33-2.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 45

RAC 8-HYDROXY EFAVIRENZ Eigenschaften

Schmelzpunkt:: 144-154°C

Siedepunkt:: 373.6±42.0 °C(Predicted)

Dichte: 1+-.0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

L?slichkeit: Acetonitrile: soluble; DMSO: soluble; Methanol: soluble

Aggregatzustand: A solid

pka: 7.18±0.40(Predicted)

Farbe: White to off-white

InChI: InChI=1S/C14H9ClF3NO3/c15-8-5-9-11(10(20)6-8)19-12(21)22-13(9,14(16,17)18)4-3-7-1-2-7/h5-7,20H,1-2H2,(H,19,21)/t13-/m0/s1

InChIKey: OOVOMPCQLMFEDT-ZDUSSCGKSA-N

SMILES: N1C2=C(O)C=C(Cl)C=C2[C@@](C#CC2CC2)(C(F)(F)F)OC1=O

Sicherheit

RAC 8-HYDROXY EFAVIRENZ Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.

Chemische Eigenschaften

Off-White Solid

Verwenden

A labellebed metabolite of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor

RAC 8-HYDROXY EFAVIRENZ Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

RAC 8-HYDROXY EFAVIRENZ Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 45)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Shanghai Devinchem Ltd	027-65318838 13646286950	sales@devinchem.com	China	2992	58
J & K SCIENTIFIC LTD.	18210857532; 18210857532	jkinfo@jkchemical.com	China	96815	76
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15402	60
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9804	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 +86-13028896684;	sales@rrkchem.com	China	57422	58

RAC 8-HYDROXY EFAVIRENZ
8-HydroxyEfavirenz
6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
(4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
Efavirenz Impurity 11(8-Hydroxy Efavirenz)
2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-
8-Hydroxy EfavirenzQ: What is 8-Hydroxy Efavirenz Q: What is the CAS Number of 8-Hydroxy Efavirenz Q: What is the storage condition of 8-Hydroxy Efavirenz Q: What are the applications of 8-Hydroxy Efavirenz
2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-
(S)-6-Chloro-4-(cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one
8-Hydroxyefavirenz/205754-33-2
8-hydroxy Efavirenz (Standard)
205754-33-2
Metabolites
Non-nucleoside Reverse Transcriptase
Pharmaceuticals
Intermediates & Fine Chemicals
Isotope Labeled Compounds

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