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C-JUN N-TERMINAL KINASE

C-JUN N-TERMINAL KINASE Struktur
CAS-Nr.
Englisch Name:
C-JUN N-TERMINAL KINASE
Synonyma:
JNK3;JNK3A;MAPK10;PRKM10;SAPK1b;p493F12;FLJ12099;FLJ33785;MGC50974;p54bSAPK
CBNumber:
CB7769250
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

C-JUN N-TERMINAL KINASE Eigenschaften

storage temp. 
−70°C
Aggregatzustand
buffered aqueous glycerol solution
Biologische Quelle
mouse

Sicherheit

S-S?tze: 23-24/25
WGK Germany  1
Speicherklasse 10 - Combustible liquids

C-JUN N-TERMINAL KINASE Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

JNK-3 is an inhibitor of JNK kinase which may be used in the treatment of many hyperactive JNK signaling diseases such as cancer, inflammatory diseases and neurodegenerative diseases.

Allgemeine Beschreibung

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. (provided by RefSeq)

C-JUN N-TERMINAL KINASE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


C-JUN N-TERMINAL KINASE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 17)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Perfect mRNA 4006682586 15252998975
rd@perfectmRNA.com China 336 58
Merck KGaA --
ordercn@merckgroup.com China 6394 58
Shanghai Yubo Biotechnology Co., Ltd 021-60514606 18321282235
sale1@shybsw.net China 8165 58
shlmai 021-67680335 13052188602
sale1@shlmai.net China 9434 58
Guangzhou Heyi Biotechnology Co., Ltd. --
CHINA 1324 58
Wuhan Bein Biotechnology Co., Ltd. --
CHINA 394 58
Huibai Biotechnology (Shenzhen) Co., Ltd. --
CHINA 1141 58
Guangzhou Suyan Biotechnology Co., Ltd --
CHINA 6927 58

  • ANTI-MAPK10 antibody produced in mouse
  • C-JUN N-TERMINAL KINASE
  • c-Jun N-Terminal Kinase from rat muscle
  • JNK3
  • SAPK1B/JNK3
  • JNK3, Stress-Activated Protein Kinase
  • FLJ33785
  • JNK3A
  • FLJ12099
  • MAPK10
  • MGC50974
  • Stress-Activated Protein Kinase
  • JNK3, active, GST tagged human
  • p493F12
  • p54bSAPK
  • PRKM10
  • SAPK1b
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