1,3-Diamino-propan Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R10:Entzündlich.
R22:Gesundheitssch?dlich beim Verschlucken.
R24:Giftig bei Berührung mit der Haut.
R35:Verursacht schwere Ver?tzungen.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S25:Berührung mit den Augen vermeiden.
S16:Von Zündquellen fernhalten - Nicht rauchen.
Chemische Eigenschaften
colourless liquid
Verwenden
1,3-Diaminopropane is commonly used in the preparation of cholinesterase inhibitors and thrombosis inhibitors. It is also used as a polymer cross linkage agent, polyurethane extender and spray coatings. It is involved in the preparation of agrochemicals and pharmaceutical intermediates. Further, it acts as a building block in the synthesis of heterocyclic compounds, which finds application in textile finishing. In addition to this, it is used as a ligand and form coordination complexes. 1,3-Diaminopropane is also utilized for the production of a chelating agent used in the photo industry and for anticorrosion agents.
Vorbereitung Methode
1,3-Diaminopropane is produced in a twostage continuous process, under a pressure of 10 – 20 MPa. In a first reactor, acrylonitrile reacts with excess ammonia at 70 – 100 ℃ to give 2-aminopropionitrile and bis(cyanoethyl) amine. The mixture of aminonitriles is then hydrogenated in a downstream reactor over a fixed-bed catalyst (cobalt or nickel) at 60 – 120 ℃ to give 1,3-diaminopropane and bis (aminopropyl)amine. The yield of 1,3- diaminopropane can be increased by adding a polar solvent and water or by using a large excess of ammonia.
Definition
ChEBI: 1,3-Diaminopropane is an alkane-alpha,omega-diamine comprising a propane skeleton with amino substituents at positions 1 and 3. It has a role as a reagent, a human metabolite and a mouse metabolite. It is a conjugate base of a trimethylenediaminium.
Allgemeine Beschreibung
Water-white mobile liquid with an odor of amine.
Air & Water Reaktionen
Highly flammable. Water soluble.
Reaktivit?t anzeigen
1,3-Diaminopropane is heat sensitive. 1,3-Diaminopropane may react with oxidizing agents.
Health Hazard
ACUTE/CHRONIC HAZARDS: 1,3-Diaminopropane is a strong irritant to eyes and skin: corrosive HAZARDOUS DECOMPOSITION PRODUCTS.
Brandgefahr
1,3-Diaminopropane is a flammable liquid.
Sicherheitsprofil
Poison by ingestion and
skin contact. Experimental teratogenic
effects. A severe skin and eye irritant.
Flammable liquid when exposed to heat,
sparks, or flame. When heated to
decomposition it emits toxic fumes of NOx.
See also AMINES.
1,3-Diamino-propan Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Cinmethylin
N-Boc-Ethylenediamine
Cocoamidopropyl betaine
dihydroxyethyl p-octadecyl phenylsulfonyl amino propyl ammoium propylsulfonate
Perhydro-1,4-diazepin
N-Boc-1,3-propanediamine
Propanenitrile, 3-[(3-aminopropyl)amino]-
2,3,4,5-TETRAHYDRO-1H-BENZO[B][1,4]DIAZEPINE
N,N'-Bis(3-aminopropyl)propan-1,3-diamin
2-(3,4-DIMETHYLPHENYL)PYRIDINE
