(R)-(+)-Etomoxir sodium salt
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- CAS-Nr.
- 828934-41-4
- Englisch Name:
- (R)-(+)-Etomoxir sodium salt
- Synonyma:
- CS-119;ANTI-EAPII;(+)-Etomoxir;Etomoxir(Nasalt);(R)-(+)-Etomoxir Na;(+)-Etomoxir sodium;Etomoxir hydrate sodium;(R)-(+)-Etomoxir Sodium;(+)-Etomoxir sodium salt;(+)-etomoxir sodium hydrate
- CBNumber:
- CB7972308
- Summenformel:
- C15H20ClNaO4
- Molgewicht:
- 322.76
- MOL-Datei:
- 828934-41-4.mol
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(R)-(+)-Etomoxir sodium salt Eigenschaften
- storage temp.
- Inert atmosphere,2-8°C
- L?slichkeit
- H2O: freely soluble
- Aggregatzustand
- White solid
- Farbe
- white
- Wasserl?slichkeit
- H2O: freely soluble
- Stabilit?t:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
- InChI
- InChI=1/C15H19ClO4.Na.H/c16-12-5-7-13(8-6-12)19-10-4-2-1-3-9-15(11-20-15)14(17)18;;/h5-8H,1-4,9-11H2,(H,17,18);;/t15-;;/s3
- InChIKey
- WENJLJJSJDAJDN-QCUBGVIVSA-M
- SMILES
- C([C@]1(OC1)C(=O)O)CCCCCOC1C=CC(Cl)=CC=1.[NaH] |&1:1,r|
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| RIDADR |
UN 2811 6.1/PG 3 |
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| WGK Germany |
3 |
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| HS Code |
2918999090 |
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| Speicherklasse |
12 - Non Combustible Liquids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
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P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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(R)-(+)-Etomoxir sodium salt Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
Verwenden
(+)-Etomoxir sodium salt hydrate has been used as an inhibitor of carnitine palmitoyltransferase 1 (CPT-1) in breast tumor cell lines and mice tumor. It has also been used as an inhibitor of fatty acid oxidation in human primary prostate epithelial cells and lymphocytes.
synthetische
Mix raw material A with solvent (tetrahydrofuran), then add catalyst, heat to a certain temperature, add p-chlorophenol, nitrogen, stirring reaction, the reaction solution is dry, remove the solvent, the resulting solid is re-dispersed in anhydrous ethanol, add sodium hydroxide solution, stirring to 30-50 ° C reaction, after the reaction is concentrated under reduced pressure, concentrate is dried, the product is produced.
Allgemeine Beschreibung
(+)-Etomoxir sodium salt hydrate belongs to oxirane carboxylic acid group of compounds and mediates metabolic channeling of fatty acid precursors. It favors oxidative stress in T cells and prevents T cell differentiation. It inhibits fatty acid oxidation and promotes hunger and food intake. Etomoxir impairs myeloid-derived suppressor cells mediated tumor and could have potential therapeutic potential.
Biochem/physiol Actions
Irreversible O-carnitine palmitoyltransferase-1 (CPT-1) inhibitor; PPARα activator
(R)-(+)-Etomoxir sodium salt Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(R)-(+)-Etomoxir sodium salt Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 135)Lieferanten
828934-41-4()Verwandte Suche:
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(Pentan-2,4-dionato-O,O')silber
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(Ethylenbis(nitrilomethylidyn)-2,2'-diphenolato)cobalt(II)
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Ethylisocyanacetat
Benzylisocyanid
Kupfer(II)-4-oxopent-2-en-2-olat
Methylisocyanacetat
2-Methylpropylisocyanid
Aluminiumtris(2,4-pentandionato-O,O')
N-Butylisocyanid
- (+)-etomoxir sodium hydrate
- r(+)-2-[6-(4-chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt hydrate
- (+)-Etomoxir hydrate sodium salt
- R(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid hydrate sodium salt
- sodium (R)-2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate
- (2R)-2-[6-(4-Chlorophenoxy)hexyl]oxiranecarboxylic acid sodium salt
- (R)-2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate sodiuM salt
or (R)-EtoMoxir, sodiuM salt
- (R)-(+)-EtoMoxir (sodiuM salt)
- (+)-Etomoxir sodium salt hydrate
- (R)-((addition))-Etomoxir sodium salt
- (+)-Etomoxir sodium salt
- sodium (S)-2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate
- Etomoxir(Nasalt)
- (R)-(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt
- ANTI-EAPII
- Etomoxir hydrate sodium
- InSolution Etomoxir - CAS 828934-41-4 - Calbiochem
- CS-119
- (R)-(+)-Etomoxir Sodium
- (+)-Etomoxir
- (R)-2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate sodium...
- (R)-(+)-Etomoxir Na
- (+)-Etomoxir sodium
- (2R)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylic acid
- Etomoxir (sodium salt), Carnitine palmitoyltransferase inhibitor
- Etomoxir sodium salt, 10 mM in DMSO
- 2-Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, sodium salt (1:1), (2R)-
- 828934-41-4
- C15H18ClO4NaH2O
- C15H18ClO4Na
- C15H18ClNaO4
