Isoxicam Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Isoxicam is a non-steroidal antiinflammatory agent useful in the treatment of
various forms of rheumatoid arthritis, osteoarthritis and musculoskeletal disorders.
It is about one-tenth as potent as its structural relative sudoxicam;
its similar long T
1/2 (>30 hrs.) allows once-daily dosing.
Verwenden
Isoxicam is used for the same indications as piroxicam. Synonyms for isoxicam are floxicam and
maxicam.
Definition
ChEBI: A monocarboxylic acid amide that is piroxicam in which the pyrid-2-yl group is replaced by a 5-methyl-1,2-oxazol-3-yl group. A non-steroidal anti-inflammatory drug, it was withdrawn from the market in the 1980s following its association with cases of Steve
s-Johnson syndrome.
Weltgesundheitsorganisation (WHO)
Isoxicam, a nonsteroidal anti-inflammatory agent, was introduced
in 1983 for the treatment of rheumatic disorders. By 1985 its use had been
associated with serious adverse effects, including four deaths from rare skin
reactions. This led to its withdrawal in France followed immediately by the
voluntary suspension of marketing worldwide by the major manufacturer.
Isoxicam Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
