CH 55

110368-33-7

CAS-Nr.: 110368-33-7

Englisch Name:: CH 55

Synonyma:: CH 55;MCE Ch55;Ch55, 10 mM in DMSO;4-[(E)-3-(3,5-Di-tert-butylphenyl)-3-oxo-1-propenyl]benzoic acid;4-[(E)-3-[3,5-Bis(tert-butyl)phenyl]-3-oxo-1-propenyl]benzoic acid;(E)-4-(3-(3,5-Di-tert-butylphenyl)-3-oxoprop-1-en-1-yl)benzoic acid;(E)-4-(3-(3,5-Bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)benzoic acid;4-[(E)-3-[3,5-Bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid;4-[(1E)-3-[3,5-BIS(1,1-DIMETHYLETHYL)PHENYL]-3-OXO-1-PROPENYL]BENZOIC ACID;Benzoic acid, 4-(3-(3,5-bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)-, (E)-

CBNumber:: CB8103738

Summenformel:: C24H28O3

Molgewicht:: 364.48

MOL-Datei:: 110368-33-7.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 73

CH 55 Eigenschaften

Schmelzpunkt:: 202-203.5 °C

Siedepunkt:: 509.5±50.0 °C(Predicted)

Dichte: 1.085±0.06 g/cm3(Predicted)

storage temp.: Store at RT

L?slichkeit: DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml; Ethanol: 5 mg/ml

Aggregatzustand: A crystalline solid

pka: 4.09±0.10(Predicted)

Farbe: White to light yellow

Stabilit?t:: Light Sensitive

Sicherheit

CH 55 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

CH 55 is a synthetic analog of retinoic acid which is an effective inhibitor of angiogenesis. Retinoids and their analogs are also promising agents for cancer chemoprevention and therapy.

Biologische Aktivit?t

Highly potent synthetic retinoid that has high affinity for RAR- α and RAR- β receptors and low affinity for cellular retinoic acid binding protein (CRABP). Inhibits rabbit tracheal epithelial cell differentiation by inhibiting transglutaminase and increasing cholesterol sulfate (EC 50 values are 0.02 and 0.03 nM respectively). Induces differentiation of embryonic carcinoma F9 and melanoma S91 cells (EC 50 values are 0.26 and 0.5 nM respectively) and inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC 50 = 1 nM).

CH 55 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CH 55 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 73)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
Shanghai Beckham Medical Technology Co., Ltd	13816613772	huahero21@sina.com	China	2826	55
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9804	58
Shanghai YuanYe Biotechnology Co., Ltd.	13636370518	shyysw007@163.com	China	89686	60
MQ (shanghai) Pharmaceuticals Co., Ltd.	13761635123	sales@linyuepharm.com	China	5664	55

CH 55
4-[(1E)-3-[3,5-BIS(1,1-DIMETHYLETHYL)PHENYL]-3-OXO-1-PROPENYL]BENZOIC ACID
4-[(E)-3-(3,5-Di-tert-butylphenyl)-3-oxo-1-propenyl]benzoic acid
4-[(E)-3-[3,5-Bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid
4-[(E)-3-[3,5-Bis(tert-butyl)phenyl]-3-oxo-1-propenyl]benzoic acid
(E)-4-(3-(3,5-Bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)benzoic acid
Benzoic acid, 4-(3-(3,5-bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)-, (E)-
Benzoic acid, 4-[(1E)-3-[3,5-bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propen-1-yl]-
(E)-4-(3-(3,5-Di-tert-butylphenyl)-3-oxoprop-1-en-1-yl)benzoic acid
Ch55, 10 mM in DMSO
MCE Ch55
110368-33-7
Intracellular receptor

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