(R)-3-Benzyloxy-Pyrrolidine Hydrochloride
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- CAS-Nr.
- 927819-90-7
- Englisch Name:
- (R)-3-Benzyloxy-Pyrrolidine Hydrochloride
- Synonyma:
- (3R)-3-benzyloxypyrrolidine;(R)-3-Benzyloxy Pyrrolidine Hcl;3-phenylmethoxypyrrolidine hydrochloride;(R)-3-BENZYLOXY-PYRROLIDINE HYDROCHLORIDE;(3R)-3-(benzyloxy)pyrrolidine hydrochloride;(R)-3-Benzyloxypyrrolidine hydrochloride - [B91084]
- CBNumber:
- CB81118928
- Summenformel:
- C11H16ClNO
- Molgewicht:
- 213.71
- MOL-Datei:
- 927819-90-7.mol
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(R)-3-Benzyloxy-Pyrrolidine Hydrochloride Eigenschaften
- storage temp.
- Sealed in dry,Room Temperature
- Aussehen
- Light yellow to brown Solid
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H332 |
Gesundheitssch?dlich bei Einatmen. |
Akute Toxizit?t inhalativ |
Kategorie 4 |
Warnung |
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P261, P271, P304+P340, P312 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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(R)-3-Benzyloxy-Pyrrolidine Hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
Synthese
After N-tert-butoxycarbonyl-(R)-3-benzyloxypyrrolidine separately obtained was dissolved in isopropanol and heated to 40 °C, isopropanol solution of hydrogen chloride was dropped for 6 hours. After the reaction finished, the mixture was cooled to 23 °C and was concentrated to distil the solvent away. Further, ethyl acetate was added and the mixture was concentrated, thereby obtaining a concentrate in an amount of about. Then, the concentrate was heated to 40 °C, and isopropanol was added until (R)-3-benzyloxypyrrolidine hydrochloride which had been separated as an oily substance became completely dissolved. After (R) -3-benzyloxypyrrolidine hydrochloride was crystallized by gradually cooling the solution and suitably adding a seed crystal, hexane was further added. At the time, crystallization solvent was in a following proportion: isopropanol/ethyl acetate/hexane = 1/71.5/71.5. A deposited crystal was subjected to filtration under reduced pressure, and the resultant wet crystal was washed with ethyl acetate, and then a wet crystal was dried under reduced pressure, thereby obtaining dry crystal of (R)-3-benzyloxypyrrolidine hydrochloride (yield of 82 %, purity of 99.8 %).
(R)-3-Benzyloxy-Pyrrolidine Hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(R)-3-Benzyloxy-Pyrrolidine Hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 48)Lieferanten
- (R)-3-Benzyloxy Pyrrolidine Hcl
- (3R)-3-(benzyloxy)pyrrolidine hydrochloride
- (3R)-3-benzyloxypyrrolidine
- 3-phenylmethoxypyrrolidine hydrochloride
- (R)-3-BENZYLOXY-PYRROLIDINE HYDROCHLORIDE
- (R)-3-Benzyloxypyrrolidine hydrochloride - [B91084]
- 927819-90-7
