Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate
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- CAS-Nr.
- 158913-22-5
- Englisch Name:
- Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate
- Synonyma:
- SPDP-C6-NHS;SPDP-C6-NHS ester;N-succinimidyl 6-(3-(2-pyridyldithio)propionamido)hexanoate;2,5-dioxopyrrolidin-1-yl 6-(3-(pyridin-2-yldisulfaneyl)propanamido)hexanoate;(2,5-dioxopyrrolidin-1-yl) 6-[3-(2-pyridyldisulfanyl)propanoylamino]hexanoate;(2,5-dioxopyrrolidin-1-yl) 6-[3-(pyridin-2-yldisulfanyl)propanoylamino]hexanoate;N-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-3-(2-pyridinyldithio)propanaMide;Hexanoic acid, 6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber:
- CB81176795
- Summenformel:
- C18H23N3O5S2
- Molgewicht:
- 425.52
- MOL-Datei:
- 158913-22-5.mol
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Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate Eigenschaften
- Schmelzpunkt:
- 82-84°C
- Dichte
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: 100 mg/mL (235.01 mM)
- pka
- 15.67±0.46(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White
- InChI
- 1S/C18H23N3O5S2/c22-14(10-13-27-28-15-6-3-5-12-20-15)19-11-4-1-2-7-18(25)26-21-16(23)8-9-17(21)24/h3,5-6,12H,1-2,4,7-11,13H2,(H,19,22)
- InChIKey
- QYEAAMBIUQLHFQ-UHFFFAOYSA-N
- SMILES
- O=C1CCC(N1OC(CCCCCNC(CCSSC2=CC=CC=N2)=O)=O)=O
Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White Solid
Allgemeine Beschreibung
The amine-reactive portion of SPDP reagents is the N-hydroxysuccinimide (NHS) ester. Reactions are most commonly performed in phosphate, carbonate/bicarbonate, or borate buffers at pH 7-8. Other buffers can be used provided they do not contain primary amines (or thiols or disulfide reducing reagents – see discussion of the sulfhydryl reactivity). The rate of reaction and degradation by hydrolysis increases with increasing pH; for example, the half-life of the NHS ester is several hours at pH 7 and less than 10 minutes at pH 9. NHS-ester reagents like SPDP and LC-SPDP have limited aqueous solubility and must be dissolved in organic solvent before adding them to a reaction mixture. Sulfo-NHS-ester reagents like Sulfo-LC-SPDP are water-soluble and can be added directly to aqueous reaction mixtures.
Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 58)Lieferanten
158913-22-5()Verwandte Suche:
- N-succinimidyl 6-(3-(2-pyridyldithio)propionamido)hexanoate
- N-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-3-(2-pyridinyldithio)propanaMide
- SPDP-C6-NHS ester
- Hexanoic acid, 6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]-, 2,5-dioxo-1-pyrrolidinyl ester
- 2,5-dioxopyrrolidin-1-yl 6-(3-(pyridin-2-yldisulfaneyl)propanamido)hexanoate
- (2,5-dioxopyrrolidin-1-yl) 6-[3-(2-pyridyldisulfanyl)propanoylamino]hexanoate
- (2,5-dioxopyrrolidin-1-yl) 6-[3-(pyridin-2-yldisulfanyl)propanoylamino]hexanoate
- SPDP-C6-NHS
- 158913-22-5
- MTS and Sulfhydryl Active Reagents
- MTS & Sulfhydryl Active Reagents
