Diethylaminoethyl Chemische Eigenschaften,Einsatz,Produktion Methoden
Originator
Aprofene,ZYF Pharm Chemical
Manufacturing Process
32 parts of α,α-diphenylpropionic acid chloride (made from diphenylpropionic
acid and thionyl chloride, B.P./12 mm 170°C) are mixed with 50 parts of
diethylaminoethanol. The mixture is heated for two hours to 150°-160°C. It is
then suspended in dilute hydrochloric acid. The solution is treated with ether.
After separation of the aqueous solution, the base is precipitated with sodium
hydroxide solution and suspended in ether.
After removal of the ether by distillation, the residue is distilled in a vacuum.
α,α-Diphenylpropionic acid β-diethylaminoethyl ester is obtained as a thick oil
by distilling under 2 mm pressure at 180°-185°C. It is readily soluble in
diluted acids.
Therapeutic Function
Spasmolytic
Diethylaminoethyl Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
