Pantoprazole Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augensch?den.
R48:Gefahr ernster Gesundheitssch?den bei l?ngerer Exposition.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Beschreibung
Pantoprazole, an irreversible proton pump inhibitor, reached its first market
worldwide in Germany for acute treatment of gastric and duodenal ulcers and
gastroesophageal reflux disease. Proton pump inhibitors are more effective than
other strategies in inhibiting acid secretion since they function at the final step of
acid production, therefore, provide superior symptom relief and healing in all acid
related diseases. As the third substituted benzimidazole proton pump inhibitor
marketed, pantoprazole not only has superior ulcer-preventing effect but also is
more potent than omeprazole in healing acetic acid-induced gastric and duodenal
ulcers with extremely low acute toxicity. The mechanism of action for this class of
compounds has been suggested to be mediated via the protonated form of the
molecule which selectively reacts with cysteines present on the extracytoplasmic
face of the enzyme to form covalent disulfide bonds.
Verwenden
proton pump inhibitor, gastric acid release inhibitor, antiulcer
Definition
ChEBI: A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.
Pantoprazole Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
