Succinylcholine Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Succinylcholine is the only therapeutically used depolarizing neuromuscular blocker.
Unlike nondepolarizing substances, succinylchloride is not a competitive antagonist; conversely,
it is a more stable agonist than acetylcholine. In this manner, succinylcholine differs
from acetylcholine only in duration—it lasts longer, causing a more stable
depolarization. Thus the process of repolarization is blocked and the muscles relax. During
this period, muscles that cause fine movement (ocular, facial, neck) are the most sensitive
and are blocked first, after which muscles of the extremities are blocked, and finally the
most stable respiratory muscles. Restoration occurs upon completion of drug action.
Verwenden
Therapeutic use of succinylcholine consists of preventing involuntary patient movement.
It is used for brief operations, intubation of the trachea, and other endoscopic procedures.
Synonyms of this drug are listenon, midarine, sucostrin, ditilin, and others.
Definition
ChEBI: A quaternary ammonium ion that is the bis-choline ester of succinic acid.
Succinylcholine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
