salutaridine Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
An alkaloid obtained from Croton salutaris, this base has been postulated as an intermediate compound in the biosynthesis of the morphine alkaloids. It yields colourless rods when crystallized from AcOEt and has [α]
D
+ 111 ° (c 1.69, EtOH). The ultraviolet spectrum in EtOH has two absorption maxima at 240 and 277 mJl. Two methoxyl groups, a phenolic hydroxyl group and a methylimino group are present, the base furnishing an O-acetate, m.p. 171°C; [α]
D + 120° (c 1.25, EtOH). More recently, it has been discovered in Croton balsamifera Jacq. and Papaver orientale.
Verwenden
Salutaridine is one of the biosynthetic precursors of morphine (M652290), a principle alkaloid of opium.
Einzelnachweise
Barton et al., J. Chem. Soc., 2423 (1965)
Battersby, Brown., Chem. Commun., 170 (1966)
Chambers, Haynes, Stuart., ibid, 449 (1966)
Mass spectra:
Wheeler, Kinstle, Rinehart.,J. Amer. Chem. Soc., 89,4494 (1967)
salutaridine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
