POLYGUANYLIC ACID (5') POTASSIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Polyguanylic acid potassium salt has been used:
- as a ligand for surface neuropilin-1 (NRP1) for internalization studies
- for intercalation studies with trisubstituted and disubstituted triazole-linked phenyl derivatives CL41, CL42 and CL2r50 using voltammetry method
- as a synthetic polynucleotide for agarose gel electrophoresis analysis
Allgemeine Beschreibung
Polyguanylic acid takes up a four-stranded helical structure. It is synthetically produced in
Thermus thermophilus from guanosine diphosphate (GDP) and its synthesis is catalyzed by the enzyme polynucleotide phosphorylase.
Biochem/physiol Actions
Polyguanylic acid acts as a ligand for scavenger receptor and reduces the surface expression neuropilin-1 in endothelial cells.
POLYGUANYLIC ACID (5') POTASSIUM SALT Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
