Anti-DCP1 Decapping enzyme 1, homolog A, Anti-Smad 4-interacting transcription factor, Anti-Smad 4-interacting transcriptional co-activator, Anti-SMAD4IP1, Anti-SMIF Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence-cell culture cells (1 paper)
Allgemeine Beschreibung
Dcp1 colocalizes with Dcp2 in distinct cytoplasmic foci along with other proteins involved in the 5′ to 3′ mRNA decay. These foci are termed PB (processing bodies) or DCP-bodies. Anti-DCP1A (C-terminal) is produced in rabbit using as immunogen a synthetic peptide corresponding to a sequence at C-terminal of human DCP1A conjugated to KLH. Two distinct genes of human DCP1 were identified, DCP1A and DCP1B, which share ~70% homology in their N-terminal and ~30% homology in their full length.
Biochem/physiol Actions
Dcp1 cleaves the m7G mRNA cap in the 5′ to 3′ mRNA decay pathway, in association with Dcp2 and Hedls complex. Decapping is a critical and highly regulated step in the turnover of mRNA which involves decapping enzymes that hydrolyze the cap structure at the 5′ mRNA.
Anti-DCP1 Decapping enzyme 1, homolog A, Anti-Smad 4-interacting transcription factor, Anti-Smad 4-interacting transcriptional co-activator, Anti-SMAD4IP1, Anti-SMIF Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
