3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester
|
|
|
- CAS-Nr.
- 7163-25-9
- Englisch Name:
- 3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester
- Synonyma:
- 3-Hydroxy-2-naphthoic acid ethyl ester;Ethyl 3-hydroxynaphthalene-2-carboxylate;3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester;3-Hydroxy-naphthalene-2-carboxylic acid ethyl ester;2-Naphthalenecarboxylic acid, 3-hydroxy-, ethyl ester
- CBNumber:
- CB82263942
- Summenformel:
- C13H12O3
- Molgewicht:
- 216.23
- MOL-Datei:
- 7163-25-9.mol
|
3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester Eigenschaften
- Schmelzpunkt:
- 79.0 to 83.0 °C
- Siedepunkt:
- 291°C(lit.)
- Dichte
- 1.1652 (rough estimate)
- Brechungsindex
- 1.5090 (estimate)
- storage temp.
- 2-8°C, stored under nitrogen
- L?slichkeit
- soluble in Toluene
- Aggregatzustand
- powder to crystal
- pka
- 9.53±0.40(Predicted)
- Farbe
- White to Orange to Green
3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthese
To a round bottom flask were added 5 g 3-hydroxy-2-naphthalic acidand 16 mL ethanol. The reaction mixture was refluxed for 6 h. After thecompletion of the reaction, the reaction mixture was cooled down to room temperature and washed with distilled water. The organic layerwas recovered and washed with saturated sodium bicarbonate followedby drying with anhydrous MgSO4. The MgSO4 was removed by filtrationand the filtrate was dried under reduced pressure. The resulted solid waspurified by silica chromatography with petroleum ether and ethyl acetate(10:1, v/v) as eluent to give the compound ethyl 3-hydroxy-2-naphthoate(4.1229 g, yield 70.60%).
3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 49)Lieferanten
- 3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester
- 3-Hydroxy-2-naphthoic acid ethyl ester
- Ethyl 3-hydroxynaphthalene-2-carboxylate
- 2-Naphthalenecarboxylic acid, 3-hydroxy-, ethyl ester
- 3-Hydroxy-naphthalene-2-carboxylic acid ethyl ester
- 7163-25-9
