Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz
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- CAS-Nr.
- 16980-89-5
- Bezeichnung:
- Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz
- Englisch Name:
- Bucladesine sodium
- Synonyma:
- Calcium Dibutyacyladenosine Cyclophosphate;DC 2797;,5ÕDBcAMP-Na;STK803270;N6-2ÕPrestwick_32;CAMP, DB-, NA;BUCLADESINE NA;dt5621sodiumsalt
- CBNumber:
- CB8236166
- Summenformel:
- C18H25N5NaO8P
- Molgewicht:
- 493.39
- MOL-Datei:
- 16980-89-5.mol
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Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz Eigenschaften
- Schmelzpunkt:
- >173°C (dec.)
- storage temp.
- -20°C
- L?slichkeit
- H2O: 50 mg/mL
- Aggregatzustand
- powder
- Farbe
- white
- Biologische Quelle
- synthetic (organic)
- Wasserl?slichkeit
- water: 1mg/mL
- Merck
- 14,1463
- Stabilit?t:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
- InChIKey
- DBXVIQJWMFGXGO-AOTDUVMNNA-N
- SMILES
- O([C@@H]1[C@]2([H])OP(O)(=O)OC[C@@]2([H])O[C@H]1N1C=NC2C(=NC=NC1=2)NC(=O)CCC)C(=O)CCC.[NaH] |&1:1,2,10,13,r|
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
24/25 |
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| WGK Germany |
2 |
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| RTECS-Nr. |
ES5055500 |
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| F |
10-21 |
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| HS Code |
29349990 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Bucladesine sodium is a derivative of cyclic-AMP with cardiac stimulant and
peripheral vasodilatory properties. It is reported to be useful in cardiac
insufficiency, especially after heart surgery.
Verwenden
Bucladesine sodium is an analog of cyclic AMP that stimulates cAMP-dependent protein kinase. It has vasodilator properties and is used as a cardiac stimulant.
Application
N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt has been used:
as a medium supplement for neural crest stem cells (NCSCs) differentiation
as a component of thawing medium for cryopreserved human iPSC (induced pluripotent stem cell)-derived neurons
in serum-free Dulbecco′s modified eagle′s medium (DMEM) to induce astrocyte differentiation
Definition
ChEBI: Bucladesine sodium is a 3',5'-cyclic purine nucleotide.
Allgemeine Beschreibung
A cell-permeable cAMP analog that preferentially activates cAMP-dependent protein kinase (PKA). Causes an increase in the steady state level of parathyroid hormone-related peptide mRNA. Also acts as a Hh pathway antagonist. Shown to induce apoptosis in vascular smooth muscle cells.
Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 409)Lieferanten
16980-89-5(Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz)Verwandte Suche:
- dibutylcyclicampsodium
- dibutylcyclicampsodiumsalt
- dt5621sodiumsalt
- e,butyrate(ester),monosodiumsalt
- monosodiumdibutyrylcyclicamp
- n-(9-beta-d-ribofuranosyl-9h-purin-6-yl)-butyramidcyclichydrogenphosphat
- n6,02’-dibutyryladenosine3’,5’-cyclicmonophosphatesodiumsalt
- n6,2’-o-dibutyryladenosine-3’,5’-cyclicmonophosphate(dbcamp),sodiumsalt
- N,2'-O-Dibutanoyladenosine 3',5'-(phosphoric acid sodium) salt
- N,2'-O-Dibutyryladenosine-3',5'-phosphoric acid sodium salt
- Sodium bucladesine
- ,5Õ
- -cyclophosphate sodium salt monohydrate
- N6-2Õ
- -O-Dibutyryl-adenosine 3Õ
- Adenosine, N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate, monosodium salt
- N6,2'-O-DIBUTYRYLADENOSINE 3':5'-CYCLIC MONOPHOSPHA
- N6,2'-O-DIBUTYRYLADENOSINE-3',5'-CYCLO-P HOSPHATE SO-SALT
- Dibutyacyladenosine
- 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adenosine deriv.
- Butyramide, N-(9-b-D-ribofuranosyl-9H-purin-6-yl)-, cyclic hydrogen phosphate butyrate (ester), monosodium salt (8CI)
- DC 2797
- Dibutyryl 3',5'-cyclic AMP sodium salt
- Dibutyryl cyclic AMP monosodium salt
- Dibutyryl cyclic AMP sodium
- N6,2'-O-Dibutyryl-3',5'-cyclic AMP sodium salt
- N6,2'-O-Dibutyryladenosine-3',5'-monophosphate monosodium salt
- N6,O2'-Dibutyryl-3',5'-cyclic AMP sodium salt
- N-6,O-2'-Dibutyryladenosine cyclic 3',5'-monophosphate sodium salt
- Sodium N6,2'-O-dibutyryladenosine 3',5'-cyclic phosphate
- DIBUTYRYL-CYCLICAMP
- BUCLADESINE[N-6,O-2''-DIBUTYRYL ADENOSINE CYCLIC 3'',5''-MONOPHOSPHATE]
- N6,2'-O-DIBUTRYL-ADENISINE-3',5'-CYCLICMONPHOSPHATE SODIUM SALT
- Bucladesine sodium salt, Dibutyryl cAMP sodium salt, Dibutyryl cyclic-AMP sodium salt
- Bucladesine, Dibutyryl cyclic-AMP
- N6,2μ-O-Dibutyryladenosine 3μ,5μ-cyclic monophosphate monohydrate sodium salt
- ibutyryl cyclic AMP sodium
- N6,O2-DIBUTYRYLADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE NA
- Dibutyacyladenosine cyclphosphate
- Adenosine,N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate, sodiuM salt(1:1)
- Adenosine 3?,5?-cyclic Monophosphate, N?,O
- Dibutyryl-cAMP sodium salt, >=98%
- adenosine,n-(1-oxobutyl)-,cyclic3’,5’-(hydrogenphosphate)-2’-butanoate,m
- bucladesinesodium
- butyramide,n-(9-beta-d-ribofuranosyl-9h-purin-6-yl)-,cyclichydrogenphosphate,butyrate(ester),monosodiumsalt
- dibutylcampsodiumsalt
- sodiumdibutyryl3’,5’-cyclicamp
- sodiumdibutyrylcamp
- N6, O2-DIBUTYRYLADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE SODIUM SALT
- N6,O2'-DIBUTYRYL ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- N6,O2'-DIBUTYRYLADENOSINE-3':5'-PHOSPHATE CYCLIC NA-SALT
- N6,O2'-DIBUTYRYLADENOSINE-3',5'-PHOSPHATE CYCLIC SODIUM SALT
- N6,2'-O-DIBUTYRYLADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- N6,2'-O-DIBUTYRYLADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- N6,2'-O-DIBUTYRYLADENOSINE-3':5'-CYCLIC MONOPHOSPHORIC ACID, SODIUM
- ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, N6,O2'-DIBUTYRYL-, SODIUM SALT
- ADENOSINE-3',5'-CYCLIC MONOPHOSPHORIC ACID, N,2'O-DIBUTYRYL, SODIUM SALT
- BUCLADESINE NA
