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Zacopride hydrochloride

Zacopride hydrochloride Struktur
101303-98-4
CAS-Nr.
101303-98-4
Englisch Name:
Zacopride hydrochloride
Synonyma:
Zacopride hydrochloride hydrate;Zacopride hydrochloride, 10 mM in DMSO;4-Amino-N-1-azabicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxybenzamide hydrochloride hydrate;IK1,5-HT Receptor,Serotonin Receptor,Zacopride hydrochloride,5-hydroxytryptamine Receptor,Zacopride,Inhibitor,5-HT4,ardiac protective,5-HT3,antiarrhythmic,inhibit
CBNumber:
CB82401236
Summenformel:
C15H21Cl2N3O2
Molgewicht:
346.25
MOL-Datei:
101303-98-4.mol

Zacopride hydrochloride Eigenschaften

Schmelzpunkt:
158-160 °C
storage temp. 
2-8°C
L?slichkeit
H2O: ≥10mg/mL
Aggregatzustand
powder
Farbe
white to tan
Wasserl?slichkeit
H2O: ≥10mg/mL
InChI
1S/C15H20ClN3O2.ClH.H2O/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19;;/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20);1H;1H2
InChIKey
NPXXKMBXEODDAF-UHFFFAOYSA-N
SMILES
O.Cl.COc1cc(N)c(Cl)cc1C(=O)NC2CN3CC[C@H]2CC3

Sicherheit

WGK Germany  3
Speicherklasse 11 - Combustible Solids

Zacopride hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Zacopride Hydrochloride, is a highly potent SR-3 antagonist and SR-4 agonist. 5-HT3 receptor antagonist. Activates IK1 channel.

Biochem/physiol Actions

Zacopride is a sub-nanomolar antagonist of the serotonin 5-HT3 receptor that also displays agonist-like activity against 5-HT4 receptors. It is a potent anxiolytic in animal models, and also has strong antiemetic effects, and also increases aldosterone levels via activation of 5-HT4 receptor in the adrenal glands.

Zacopride hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Zacopride hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 40)Lieferanten
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ATK CHEMICAL COMPANY LIMITED
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Aladdin Scientific

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Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9804 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847 13636370518
shyysw007@163.com China 89686 60

  • 4-Amino-N-1-azabicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxybenzamide hydrochloride hydrate
  • Zacopride hydrochloride hydrate
  • IK1,5-HT Receptor,Serotonin Receptor,Zacopride hydrochloride,5-hydroxytryptamine Receptor,Zacopride,Inhibitor,5-HT4,ardiac protective,5-HT3,antiarrhythmic,inhibit
  • Zacopride hydrochloride, 10 mM in DMSO
  • 101303-98-4
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