Y-27632 dihydrochloride

129830-38-2

CAS-Nr.: 129830-38-2

Englisch Name:: Y-27632 dihydrochloride

Synonyma:: CS-1919;Y27632 HCl;Y-27633 (2 HCl);27632 (hydrochloride);Y27632 (hydrochloride);Y-27632 DIHYDROCHLORIDE;Y-27632; Y27632; Y 27632;Y-27632, Sterile-Filtered;Y-27632 dihydrochloride, >=98%;Y-27632 dihydrochloride Y27632

CBNumber:: CB82526054

Summenformel:: C14H23Cl2N3O

Molgewicht:: 320.25792

MOL-Datei:: 129830-38-2.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 227

Y-27632 dihydrochloride Eigenschaften

Schmelzpunkt:: 258℃

storage temp.: 2-8°C

L?slichkeit: H2O: soluble14mg/mL

Aggregatzustand: powder

Farbe: white to beige

Biologische Quelle: synthetic (organic)

Optische Rotation: [α]/D +3.0 to +5.0°, c =1.0 in methanol

Wasserl?slichkeit: H2O: 14mg/mL

Stabilit?t:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20° for up to 3 months.

InChI: InChI=1/C14H21N3O.2ClH/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13;;/h6-12H,2-5,15H2,1H3,(H,16,17,18);2*1H/t10-,11,12;;/s3

InChIKey: IDDDVXIUIXWAGJ-MEIAXHMCNA-N

SMILES: C1(C(NC2=CC=NC=C2)=O)CCC([C@H](N)C)CC1.[H]Cl.[H]Cl |&1:13,r|

Sicherheit

Kennzeichnung gef?hrlicher	Xn
R-S?tze:	20/21/22
S-S?tze:	36
WGK Germany	3
HS Code	29333990
Speicherklasse	11 - Combustible Solids

Y-27632 dihydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

A cell permeable inhibitor of ROCK-1 and ROCK-2

Allgemeine Beschreibung

Y-27632 dihydrochloride is an effective bronchodilator and improves lung resistance (RL) induced by antigen and acetylcholine. Y-27632 controls neutrophil migration and lung edema and may be a potential drug for treating acute lung injury.

Biochem/physiol Actions

Y-27632 is highly potent, cell-permeable, selective ROCK (Rho-associated coiled coil forming protein serine/threonine kinase) inhibitor. Ki = 140 nM for p160ROCK. Y-27632 also inhibits ROCK-II with equal potency. The inhibition is competitive with respect to ATP.

Y-27632 dihydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Y-27632 dihydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 227)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	965	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Dideu Industries Group Limited	+86-86-15536356810 +8617392712697	1022@dideu.com	China	28760	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58

(R)-4-(1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride
Y-27632 DIHYDROCHLORIDE;ROCK INHIBITOR
Y-27632 dihydrochloride, >=98%
trans-4-[(R)-1-Aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride Y 27632 dihydrochloride
Y 27632 dihydrochloride (+)-trans-N-(4-Pyridyl)-4-[(R)-1-aminoethyl]cyclohexanecarboxamide dihydrochloride
Y27632 (hydrochloride)
(+)-trans-N-(4-Pyridyl)-4-[(R)-1-aminoethyl]cyclohexanecarboxamide dihydrochloride
trans-4-[(R)-1-Aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride
Y27632 HCl
Y-27632, Dihydrochloride Salt, >99%
Y-27632; Y27632; Y 27632
CS-1919
Y-27632; Y27632; Y 27632;Y 27632 DIHYDROCHLORIDE;Y27632 DIHYDROCHLORIDE
Y-27632 dihydrochloride, 98.5%, a selective ROCK1 (p160ROCK) inhibitor
trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride
Y27632 (hydrochloride) USP/EP/BP
Trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride (Y-27632 dihydrochloride)
Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, hydrochloride (1:2), trans-
Y-27632 dihydrochloride Y27632
27632 (hydrochloride)
Y-27632 dihydrochloride (mM/ml), Rho kinase inhibitor
Y-27632, Sterile-Filtered
Y-27632 dihydrochloride, Rho kinase inhibitor
Y-27632 in solution New
Y-27632 dihydrochloride, 10 mM in DMSO
Abmole M1817-100mg Y-27632 dihydrochloride 129830-38-2
Y-27632 DIHYDROCHLORIDE
Y-27633 (2 HCl)
129830-38-2
Csub1subsub4subHsub2subsub1subNsub3subO2HCl
Inhibitors
APIs

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