tert-Butyl 3-(2-hydroxyethoxy)propanoate
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- CAS-Nr.
- 671802-00-9
- Englisch Name:
- tert-Butyl 3-(2-hydroxyethoxy)propanoate
- Synonyma:
- OH-PEG1-TBA;OH-PEG1-COOtBu;HO-PEG1-CH2CH2COOTBU;OH-PEG1-CH2CH2COOtBu;HO-PEG1-t-Butyl ester;Hydroxy-PEG1-(CH2)2-Boc;Alcohol-PEG2-t-Bu Ester;Hydroxy-PEG1-t-butyl ester;tert-Butyl 3-(2-hydroxyethoxy)propanoate;2-Methyl-2-propanyl 3-(2-hydroxyethoxy)propanoate
- CBNumber:
- CB82680372
- Summenformel:
- C9H18O4
- Molgewicht:
- 190.24
- MOL-Datei:
- 671802-00-9.mol
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tert-Butyl 3-(2-hydroxyethoxy)propanoate Eigenschaften
- Siedepunkt:
- 274.0±15.0 °C(Predicted)
- Dichte
- 1.031±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 14.36±0.10(Predicted)
- Aggregatzustand
- liquid
- Farbe
- Yellowish
- Wasserl?slichkeit
- Water: 100 mg/mL (525.65 mM)
- InChI
- InChI=1S/C9H18O4/c1-9(2,3)13-8(11)4-6-12-7-5-10/h10H,4-7H2,1-3H3
- InChIKey
- ACWLDITVZGWIKA-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)CCOCCO
tert-Butyl 3-(2-hydroxyethoxy)propanoate Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
tert-Butyl 3-(2-hydroxyethoxy)propanoate is a reactant in the synthesis of hydrophilic aminooxy linked and multivalent disaccharide cellobiose derivatives for chemoselective aldehyde/ketone conjugation
Synthese
To a solution of anhydrous ethylene glycol (10 g, 161.1 mmol) in anhydrous THF (40 mL) was added sodium metal (62.0 mg, 2.70 mmol) and stirred at room temperature for 2 hours.Add tert-butyl acrylate (6.90, 53.7 mmol) and stir overnight.After quenching with water, the solvent was THF dried under reduced pressure, and extracted with ethyl acetate and water.The organic layer was separated, washed with brine, and dried over Na 2 SO 4.After filtration and evaporation, the residue was purified by silica gel column chromatography (petroleum ether/ethyl acetate = 2:1) to obtain a colorless oil 44 (5.0 g, 26.3 mmol, 49% yield)
tert-Butyl 3-(2-hydroxyethoxy)propanoate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
tert-Butyl 3-(2-hydroxyethoxy)propanoate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 116)Lieferanten
- tert-Butyl 3-(2-hydroxyethoxy)propanoate
- HO-PEG1-CH2CH2COOTBU
- Hydroxy-PEG1-t-butyl ester
- 3-(2-Hydroxyethoxy)propanoic acid 1,1-dimethylethyl ester
- 3-(2-Hydroxyethoxy)propanoic acid tert-butyl ester
- HO-PEG1-t-Butyl ester
- OH-PEG1-CH2CH2COOtBu
- Hydroxy-PEG1-(CH2)2-Boc
- 3-(2-hydroxyethoxy)propionic acid tert-butyl ester
- Propanoic acid, 3-(2-hydroxyethoxy)-, 1,1-dimethylethyl ester
- 2-Methyl-2-propanyl 3-(2-hydroxyethoxy)propanoate
- OH-PEG1-TBA
- OH-PEG1-COOtBu
- Alcohol-PEG2-t-Bu Ester
- 671802-00-9
- peg
