Ebastine
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- CAS-Nr.
- 90729-43-4
- Englisch Name:
- Ebastine
- Synonyma:
- EBASTIN;LAS-90;EBASTEL;Ebasine;Estivan;EVASTEL;KESTINE;ebastina;RP 64305;EBASTINE
- CBNumber:
- CB8271800
- Summenformel:
- C32H39NO2
- Molgewicht:
- 469.66
- MOL-Datei:
- 90729-43-4.mol
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Ebastine Eigenschaften
- Schmelzpunkt:
- 80-82°C
- Siedepunkt:
- 596.3±50.0 °C(Predicted)
- Dichte
- 1.09±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- Slightly soluble in chloroform, methanol.
- pka
- 8.19±0.10(Predicted)
- Aggregatzustand
- solid
- Farbe
- white
- Merck
- 14,3484
- InChIKey
- MJJALKDDGIKVBE-UHFFFAOYSA-N
- SMILES
- C(C1=CC=C(C(C)(C)C)C=C1)(=O)CCCN1CCC(OC(C2=CC=CC=C2)C2=CC=CC=C2)CC1
- CAS Datenbank
- 90729-43-4(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| RTECS-Nr. |
EL8140000 |
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| HS Code |
2933.39.9200 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H303 |
May be harmfulif swallowed |
Acute toxicity,oral |
Category 5 |
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P312 |
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| Sicherheit |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P403 |
An einem gut belüfteten Ort aufbewahren. |
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Ebastine Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Ebastine is a new once-daily histamine Hl-receptor antagonist with no sedative
effects or autonomic impairment at therapeutic doses. It is reported to be effective
in the treatment of hay fever, perennial rhinitis, and uticaria. Ebastine's
antihistamine activity is attributed to its carboxylic acid metabolite carebastine.
Chemische Eigenschaften
White to Off-White Powder
Verwenden
Ebastine is a second-generation H1 receptor antagonist that is indicated mainly for allergic rhinitis and chronic idiopathic urticaria. It is available in 10 and 20 mg tablets and as fast-dissolving tablets, as well as in pediatric syrup. It has a recommended flexible daily dose of 10 or 20 mg, depending on disease severity.
Allgemeine Beschreibung
Ebastine is metabolised by cytochrome P450 3A (CYP3A4) to carebastine. It is used to treat allergic rhinitis and chronic idiopathic urticaria.
Ebastine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Ebastine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 429)Lieferanten
90729-43-4()Verwandte Suche:
- 4'-(1,1-Dimethylethyl)-γ-[4-(diphenylmethoxy)piperidin-1-yl]butyrophenone
- 4'-tert-Butyl-γ-[4-(diphenylmethoxy)piperidino]butyrophenone
- Ebastel-OD
- IMp. A (EP): DiphenylMethanol (Benzhydrol)
- Ebastine Impurity
- 1-butanone,1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidiny
- 4’-tert-butyl-4-(4-(diphenylmethoxy)piperidino)butyrophenone
- 4-diphenylmethoxy-1-(3-(4-tert-butylbenzoyl)propyl)piperidine
- ebastina
- Ebasine
- EBASTINE, REFERENCE SPECTRUM EP STANDARD
- EBASTINE, IMPURITY C4-(DIPHENYLMETHOXY)PIPERIDINE EP STANDARD
- EBASTINE, MM STANDARD
- EBASTINE, IMPURITY D1-[4-(1,1-DIMETHYLETHYL)PHENYL]-4-(4-HYDROXYPIPERIDIN-1-YL)BUTAN-1-ONE EP STANDARD
- 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone
- Estivan
- LAS-W 090
- RP 64305
- LAS-W-090：Bastd
- 4-(4-benzhydryloxy-1-piperidyl)-1-(4-tert-butylphenyl)butan-1-one
- EBASTINE
- EVASTEL
- KESTINE
- 1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-buta
- Ebastine CRS
- Ebastine>
- 1-Butanone, 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-
- Ebastine USP/EP/BP
- Ebastine (LAS-W 090
- Ebastine D6
- EbastineQ: What is
Ebastine Q: What is the CAS Number of
Ebastine Q: What is the storage condition of
Ebastine Q: What are the applications of
Ebastine
- Ebastine (1231207)
- EBASTEL
- EBATINE IP/ BP
- 4-[4-(Benzhydryloxy)-1-piperidyl]-1-[4-(tert-butyl)phenyl]-1-butanone
- Ibastatin
- Ebasidine
- Ebastel|||LAS-W 090|||Ebastin|||Kestine|||RP64305
- Ebastine, 10 mM in DMSO
- Ebastine - Bio-X ?
- Ebastine (Standard)
- EBASTIN
- LAS-90
- 90729-43-4
- 90729-49-4
- C32H39NO2
- Inhibitors
- Active Pharmaceutical Ingredients
- Intermediates & Fine Chemicals
- Pharmaceuticals
- 90729-43-4
