MI-136

1628316-74-4

CAS-Nr.: 1628316-74-4

Englisch Name:: MI-136

Synonyma:: MI-136;CS-2162;MI136;MI 136;HY-19319 (MI 136;MI-136, 10 mM in DMSO;MI-136;HY-19319 (MI 136; MI136);;5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-in;5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-indole-2-carbonitrile;5-[[4-[[6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1H-indole-2-carbonitrile;1H-Indole-2-carbonitrile, 5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-

CBNumber:: CB83121119

Summenformel:: C23H21F3N6S

Molgewicht:: 470.51

MOL-Datei:: 1628316-74-4.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 84

MI-136 Eigenschaften

Siedepunkt:: 654.9±55.0 °C(Predicted)

Dichte: 1.45±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

L?slichkeit: DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 10 mg/ml

Aggregatzustand: A crystalline solid

pka: 14.20±0.30(Predicted)

Farbe: White to off-white

Sicherheit

MI-136 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

MI-136 is an inhibitor of the menin-MLL interaction (IC₅₀ = 31 nM; K_d = 23.6 nM). By blocking MLL recruitment predominantly at the level of the menin-MLL interaction, it can inhibit androgen receptor (AR)-mediated transcription. At 40 mg/kg, MI-136 has been shown to block AR signaling, inhibiting the growth of castration-resistant tumors in mice.

MI-136 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

MI-136 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 84)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39039	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11680	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43333	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42056	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	5221	58

1628316-74-4()Verwandte Suche:

Ceftazidim

MI-136
MI-136;HY-19319 (MI 136; MI136);
HY-19319 (MI 136
1H-Indole-2-carbonitrile, 5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-
5-[[4-[[6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1H-indole-2-carbonitrile
5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-in
MI136;MI 136
CS-2162
PPI,MI 136,Apoptosis,inhibit,MI136,Inhibitor,CRPC,castration,cancer,resistant,MI-136,Androgen Receptor,Epigenetic Reader Domain,prostate
5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-indole-2-carbonitrile
MI-136, 10 mM in DMSO
1628316-74-4
C23H21F3N6S

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