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ACE 031

ACE 031 Struktur
CAS-Nr.
Englisch Name:
ACE 031
Synonyma:
ACE 031
CBNumber:
CB83123133
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ACE 031 Eigenschaften

Sicherheit

ACE 031 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

ACE 031 is a muscle modulator that combines with myostatin and other negative regulators of muscle mass to promote muscle growth. It is a fusion protein of activin receptor type IIB (ActRIIB) and IgG1-Fc that binds to myostatin and related ligands. Clinical studies have shown that ACE 031 can be used to treat myopathies such as Duchenne muscular dystrophy (DMD).

Einzelnachweise

[1] Craig Campbell. “Myostatin inhibitor ACE-031 treatment of ambulatory boys with Duchenne muscular dystrophy: Results of a randomized, placebo-controlled clinical trial.” Muscle & Nerve 55 4 (2017): 458–464.
[2] Joonho Suh, Yun-Sil Lee. “Myostatin Inhibitors: Panacea or Predicament for Musculoskeletal Disorders” Journal of Bone Metabolism 27 3 (2020): 151–165.

ACE 031 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


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