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Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat)

EC 1.1.1.42 Struktur
9028-48-2
CAS-Nr.
9028-48-2
Bezeichnung:
Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat)
Englisch Name:
EC 1.1.1.42
Synonyma:
IDH;IDH1;ICDH;IDHM;IDPM;IDCD;PICD;ICD-M;D2HGA2;HEL-216
CBNumber:
CB8395171
Summenformel:
NULL
Molgewicht:
0
MOL-Datei:
Mol file

Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat) Eigenschaften

storage temp. 
2-8°C
Aggregatzustand
solution (clear)
Farbe
yellow-brown
Biologische Quelle
Porcine heart
Specific Activity
3-20units/mg protein
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
10
HS Code  3507909090
Speicherklasse 10 - Combustible liquids
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.

Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat) Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Human Isocitrate Dehydrogenase (IDH1) is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It may be useful as a biomarker for diagnosis and prognosis prediction of non-small cell lung cancer .

Allgemeine Beschreibung

Isocitrate dehydrogenase 1 (IDH1) gene is located on human chromosome 2q33. IDH1 is present in the cytoplasm and peroxisomes. It is expressed at high levels in the mammalian liver. IDH1 consists of a C-terminal tripeptide peroxisome, that targets the signal one sequence.

Biochem/physiol Actions

Isocitrate dehydrogenase 1 (IDH1) help in the oxidative carboxylation of isocitrate to α-ketoglutarate, that results in the formation of reduced nicotinamide adenine dinucleotide phosphate (NADPH). It participates in lipid metabolism and glucose sensing. Suppressing IDH1 in pancreatic islets affects the insulin secretion, induced by glucose and leads to increase in lactate production.

Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 94)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
career henan chemical co
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sales@coreychem.com China 29815 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19936 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49979 58
Creative Enzymes
1-516-855-7709
info@creative-enzymes.com United States 8748 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8615965530500
nickzhang@hangyubiotech.com China 9949 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850
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+86-2759207851; +8618007136271
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+86-023-6139-8061 +86-86-13650506873
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J & K SCIENTIFIC LTD. 18210857532; 18210857532
jkinfo@jkchemical.com China 96815 76
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097
sales.bj@hwrkchemical.com China 9416 55

9028-48-2(Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat))Verwandte Suche:


  • THREO-DS-ISOCITRATE: NADP+ OXIDOREDUCTASE
  • THREO-DS-ISOCITRATE: NADP(+) OXIDOREDUCTASE[DECARBOXYLATING]
  • THREO-DS-ISOCITRATE: NADP(+) OXIDOREDUCTASE[DECARBOXYLATING] TYPE I
  • THREO-DS-ISOCITRATE: NADP(+) OXIDOREDUCTASE[DECARBOXYLATING] TYPE IV
  • isocitrate dehydrogenase from porcine heart
  • ICDH
  • ISOCITRIC DEHYDROGENASE (NADP)
  • ISOCITRIC DEHYDROGENASE (NADP) TYPE I
  • ISOCITRIC DEHYDROGENASE (NADP) TYPE IV
  • ISOCITRATE DEHYDROGENASE
  • EC 1.1.1.42
  • EC 1.1.1.42 TYPE I
  • EC 1.1.1.42 TYPE IV
  • ISOCITRAT DEHYDROGENASE FROM PORCINE HEA RT, 3-8 U/MG
  • ISOCITRIC DEHYDROGENASE TYPE IV FROM*POR CINE HEART
  • ISOCITRATE DEHYDROGENASE FROM PORCINE HE ART, ~10 U/MG
  • ISOCITRIC DEHYDROGENASE TYPE I CRUDE*FRO M PORCINE H
  • isocitric dehydrogenase (nadp) from porcine heart
  • Recombinant Isocitrate Dehydrogenase
  • isocitric dehydrogenase
  • ICDH, threo-Ds-Isocitrate: NADP+ oxidoreductase
  • Isocitric Dehydrogenase (NADP) from porcine heart,threo-Ds-Isocitrate: NADP+ oxidoreductase, ICDH
  • Isocitrate dehydrogenase (NAD+) recombinant from Yeast, 50% glycerol solution
  • rICDH (NADP), threo-Ds-Isocitrate: NAD oxidoreductase (decarboxylating)
  • rICDH (NAD), threo-Ds-Isocitrate: NAD oxidoreductase (decarboxylating)
  • IsoCltrate dehydrogenase
  • TPN-specific isocitrate dehydrogenase
  • TPN-linked isocitrate dehydrogenase
  • TPN-isocitrate dehydrogenase
  • TPN-dependent isocitrate dehydrogenase
  • Oxalosuccinic decarboxylase
  • Isocitrate Dehydrogenase preparation porcine heart
  • isocitric dehydrogenase type I crude*from porcine
  • Dehydrogenase, isocitrate (nicotinamide adenine dinucleotide phosphate)
  • ISOCITRIC DEHYDROGENASE HIGHLY PURIFIED FROM PORCIN
  • Isocitrate Dehydrogenase 1 (NADP+) huMan
  • Isocitrate Dehydrogenase Cytoplasmic
  • MGC171441
  • MGC174090
  • MGC55806
  • Isocitric Dehydrogenase (NADP), Bacillus subtilis, recombinant from E. coli
  • NADP-specific isocitric dehydyrogenase
  • NADPH-dependent isocitrate dehydrogenase
  • Isocitrate Dehydrogenase (NADP+) from Bacteria, Recombinant
  • Native Porcine Isocitric Dehydrogenase (NADP)
  • Isocitrate Dehydrogenase (NADP+) from Yeast, Recombinant
  • Recombinant Human IDH1 C-his8 Protein, His Tag
  • Recombinant Human IDH1 Protein, His Tag
  • Isocitrate dehydrogenase from Bacillus subtilis, Recombinant
  • :THREO-DS-ISOCITRATE
  • Isocitrate dehydrogenas
  • Isocitric Dehydrogenase (NADP) from porcine heart Type IV, buffered aqueous glycerol solution, 3-20 units/mg protein
  • Isocitrate Dehydrogenase Activity Microplate Assay Kit
  • Recombinant Human IDH1 Protein (R132H, C-8His)
  • IDHM
  • IDPM
  • mNADP-IDH
  • D2HGA2
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