4-Hydroxybutan-2-on
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- CAS-Nr.
- 590-90-9
- Bezeichnung:
- 4-Hydroxybutan-2-on
- Englisch Name:
- 4-Hydroxy-2-butanone
- Synonyma:
- 4-hydroxybutan-2-one;CH3C(O)CH2CH2OH;Methylolacetone;2-Butanone, 4-hydroxy-;3-Oxobutanol;Butanone glycol;3-Ketobutan-1-ol;Monomethylolacetone;H**4-HYDROXY-2-BUTANONE;ketobutanol
- CBNumber:
- CB8493505
- Summenformel:
- C4H8O2
- Molgewicht:
- 88.11
- MOL-Datei:
- 590-90-9.mol
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4-Hydroxybutan-2-on Eigenschaften
- Schmelzpunkt:
- 15°C (estimate)
- Siedepunkt:
- 73-76 °C/12 mmHg (lit.)
- Dichte
- 1.023 g/mL at 25 °C (lit.)
- Brechungsindex
- 1.430
- Flammpunkt:
- 91°F
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- L?slichkeit
- Chloroform, Methanol (Slightly)
- pka
- 14.43±0.10(Predicted)
- Aggregatzustand
- Oil
- Farbe
- Clear Colourless
- Wasserl?slichkeit
- Miscible with water, alcohol, ethanol and ether.
- BRN
- 1737666
- InChI
- 1S/C4H8O2/c1-4(6)2-3-5/h5H,2-3H2,1H3
- InChIKey
- LVSQXDHWDCMMRJ-UHFFFAOYSA-N
- SMILES
- CC(=O)CCO
- LogP
- -1.209 at 25℃
- CAS Datenbank
- 590-90-9(CAS DataBase Reference)
- NIST chemische Informationen
- 4-Hydroxy-2-butanone(590-90-9)
- EPA chemische Informationen
- 2-Butanone, 4-hydroxy- (590-90-9)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| R-S?tze: |
10 |
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| S-S?tze: |
16-24/25 |
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| RIDADR |
UN 1993 |
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| WGK Germany |
3 |
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| TSCA |
TSCA listed |
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| HazardClass |
3 |
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| HS Code |
29144000 |
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| Speicherklasse |
3 - Flammable liquids |
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| Hazard Classifications |
Flam. Liq. 3 |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H226 |
Flüssigkeit und Dampf entzündbar. |
Entzündbare Flüssigkeiten |
Kategorie 3 |
Warnung |
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| H227 |
Combustible liquid |
Flammable liquids |
Category 4 |
Warnung |
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P210, P280, P370+P378, P403+P235,P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
| P405 |
Unter Verschluss aufbewahren. |
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4-Hydroxybutan-2-on Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R10:Entzündlich.
S-S?tze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
Chemische Eigenschaften
Colourless to pale yellow liquid
Verwenden
4-Hydroxy-2-butanone is used in the preparation of fused benzazepine molecules as selective D3 receptor antagonists with pharmaceutical activity. It is also used in the preparation of verrucarin and mevalonic acid lactone. Further, it is used to prepare 3-buten-2-one through dehydration over an anatase titanium dioxide catalyst. It is also employed in the preparation of 4-methyl-5-hydroxymethylthiazole, (±)-lineatin and beta-hydroxylactones.
Definition
ChEBI: A beta-hydroxy ketone that is butan-2-one substituted by a hydroxy group at position 4.
Application
4-Hydroxy-2-butanone has been used in the synthesis of:
- 3-buten-2-one via dehydration over anatase-TiO2 catalyst
- 4-methyl-5-hydroxymethylthiazole
- (±)-lineatin
- mevalonic acid lactone
- verrucarin
- β-hydroxylactones
Allgemeine Beschreibung
4-Hydroxy-2-butanone is an important pharmaceutical intermediate. Gas phase reaction of the OH radicals with 4-hydroxy-2-butanone has been investigated by absolute rate method.
4-Hydroxybutan-2-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Hydroxybutan-2-on Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 353)Lieferanten
590-90-9(4-Hydroxybutan-2-on)Verwandte Suche:
- 2-Butanone,4-hydroxy-
- 3-Oxo-1-butanol
- 4-Butanol-2-one
- 4-hydroxy-2-butanon
- 4-HYDROXY-2-BUTANONE
- 2-HYDROXYETHYL METHYL KETONE
- 4-Hydroxy-2-butanone,95%
- ketobutanol
- 1-Hydroxy-3-butanone
- Hydroxy-2-butan
- 4-Hydroxy-2-butanone , 95.0%(GC)
- 4-hydrxy-2-butone
- 4-Hydroxy-2-butanone >
- 3-Ketobutan-1-ol
- H**4-HYDROXY-2-BUTANONE
- Butanone glycol
- 2-Butanone, 4-hydroxy-
- 3-Oxobutanol
- Ethyl Acetate Impurity 195
- 4-hydroxybutan-2-one
- CH3C(O)CH2CH2OH
- Methylolacetone
- Monomethylolacetone
- 590-90-9
- 590-50-9
- HOCH2CH2COCH3
- KETONE
- Organic Building Blocks
- Ketones
- Carbonyl Compounds
- C3 to C6
- Building Blocks
- in-stock
- straight chain compounds
- ketone
- 1
- bc0001
- 590-90-9
- john's
