Silicristin
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- CAS-Nr.
- 33889-69-9
- Bezeichnung:
- Silicristin
- Englisch Name:
- Silychristin
- Synonyma:
- Silicristin;SILICHRISTIN;Silychristin A;SILYCRISTIN;Silymarin II;SILYCHRISTIN;Christianity;Silychristin，SC;Silychristin-RM;SILYCHRISTIN hplc
- CBNumber:
- CB8687836
- Summenformel:
- C25H22O10
- Molgewicht:
- 482.44
- MOL-Datei:
- 33889-69-9.mol
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Silicristin Eigenschaften
- Schmelzpunkt:
- 174～176℃
- Siedepunkt:
- 782.0±60.0 °C(Predicted)
- Dichte
- 1.578±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- Acetone (Slightly), Methanol (Slightly)
- pka
- 7.39±0.60(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Wasserl?slichkeit
- practically insoluble in water
- Stabilit?t:
- Hygroscopic
- InChIKey
- BMLIIPOXVWESJG-LMBCONBSSA-N
- SMILES
- COc1cc(ccc1O)[C@@H]2Oc3c(O)cc(cc3[C@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| S-S?tze: |
22-45 |
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| WGK Germany |
3 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Acute Tox. 4 Oral |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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Silicristin Chemische Eigenschaften,Einsatz,Produktion Methoden
Definition
ChEBI: A flavonolignan isolated from Silybum marianum and has been shown to exhibit inhibitory activities against lipoxygenase and prostaglandin synthetase.
in vitro
Silychristin exhibits a strong inhibition of MCT8-mediated T3 uptake with an IC50 of 110 nM in MCT8 overexpressing MDCK1-cells.
It causes no cytotoxic for fibroblasts.
Silychristin (6.5-75 μM; 24 hours) diminishes UVA toxicity and reduces ROS generation, and the protective effect is dose-dependent.
Silychristin (12.5μM, 25μM) reduces the metalloproteinase-1 (MMP-1) level in cells.
target
MCT8
Silicristin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Silicristin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 234)Lieferanten
33889-69-9(Silicristin)Verwandte Suche:
Silibinin
Milk thistle P.E
3,6-Bis[(4-chlor-2-phosphonophenyl)azo]-4,5-dihydroxynaphthalin-2,7-disulfonsure
SILIBININ-N-METHYLGLUCAMINE, 95％ （HPLC）
Silidianin
trans-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol
p-(Benzyloxy)phenethylalkohol
Cianidanol
(S)-2,3-Dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-4-benzopyron
trans-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-3,7-dihydroxy-4-benzopyron
(S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4-benzopyron
3-(4-Methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-on
Silicristin
- SILYCHRISTIN
- SILYCRISTIN
- SILYCHRISTIN hplc
- 4H-1-Benzopyran-4-one,2-[(2R, 3S)-2,3-dihydro-7-
- hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-benzofuranyl]-2,3-dihydro-3,5,7-trihydroxy-,(2R,3R)-
- Silymarin II
- (2R,3R)-3,5,7-Trihydroxy-2-[(2R,3S)-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1-benzofuran-5-yl]chroman-4-one
- Silicristin, SilyMarin II
- 4H-1-Benzopyran-4-one,2-[(2R,3S)-2,3-dihydro-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-benzofuranyl]-2,3-dihydro-3,5,7-trihydroxy-,(2R,3R)-
- Silychristin, 98%, from Silybum marianum (L.) Gaertn.
- Silychristin，SC
- Silicristin USP/EP/BP
- Christianity
- (2R,3R)-3,5,7-Trihydroxy-2-((2R,3S)-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydrobenzofuran-5-yl)chroman-4-one
- Silychristin-RM
- Silychristin, 10 mM in DMSO
- Silychristin (Standard)
- SILICHRISTIN
- Silicristin
- Silychristin A
- 33889-69-9
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Miscellaneous Natural Products
