7-Bromobenz[A]Anthracene
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- CAS-Nr.
- 32795-84-9
- Englisch Name:
- 7-Bromobenz[A]Anthracene
- Synonyma:
- 7-Bromotetraphene;Bromobenzanthracene;7-bromobenzanthracene;7-BROMOBENZ[A]ANTHRACENE;7-bromo-benz(a)anthracen;10-brom-1,2-benzanthracen;7-bromobenzo[a]anthracene;10-bromo-1,2-benzanthracene;Benz[a]anthracene, 7-bromo-;7-Bromobenz[a]anthracene >
- CBNumber:
- CB8710123
- Summenformel:
- C18H11Br
- Molgewicht:
- 307.18
- MOL-Datei:
- 32795-84-9.mol
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7-Bromobenz[A]Anthracene Eigenschaften
- Schmelzpunkt:
- 152 °C
- Siedepunkt:
- 361.79°C (rough estimate)
- Dichte
- 1.3995 (rough estimate)
- Brechungsindex
- 1.6000 (estimate)
- storage temp.
- Room Temperature, under inert atmosphere
- L?slichkeit
- Chloroform (Slightly), Dichloromethane (Slightly)
- Aggregatzustand
- Solid
- Farbe
- Light Beige to Dark Yellow
- InChI
- InChI=1S/C18H11Br/c19-18-15-8-4-2-6-13(15)11-17-14-7-3-1-5-12(14)9-10-16(17)18/h1-11H
- InChIKey
- LGRNWCDRODWMOH-UHFFFAOYSA-N
- SMILES
- C12=CC=CC=C1C=CC1C2=CC2C(=CC=CC=2)C=1Br
7-Bromobenz[A]Anthracene Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
7-Bromobenzo[A]anthracene is an organic synthesis intermediate, particularly used in the pharmaceutical and fine chemical industries to construct complex aromatic compounds.
Toxicity evaluation
The tumorigenicity of 7-chlorobenz[α]anthracene (7-C1-BA), an environmental contaminant, and 7-bromobenz[α]anthracene (7-Br-BA) was determined in the male B6C3F1 newborn mouse. Mice receiving 7-C1-BA and 7-Br-BA by i.p. injections at a dose of 1600 nmol per mouse on 1, 8, and 15 days after birth developed 92 and 96% hepatocellular adenomas, and 100 and 83% hepatocellular carcinoma, respectively. Metabolism by liver microsomes of 15-day-old mice each produced the corresponding trans-3,4-dihydrodiol. Analysis by 32P-postlabeling/HPLC indicated the presence of DNA adducts derived from 7-C1-BA trans-3,4-dihydrodiol and 7-Br-BA trans-3,4-dihydrodiol. The results indicate that both 7-C1-BA and 7-Br-BA are potent carcinogens and that bay-region diol epoxides are the ultimate metabolites that lead to DNA adduct formation and tumor initiation[1].
7-Bromobenz[A]Anthracene Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
7-Bromobenz[A]Anthracene Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 82)Lieferanten
32795-84-9()Verwandte Suche:
- 10-brom-1,2-benzanthracen
- 10-bromo-1,2-benzanthracene
- 7-bromo-benz(a)anthracen
- 7-bromobenzanthracene
- 7-BROMO-BENZ[A]ANTHRACENE 98+%
- 7-BROMOBENZ[A]ANTHRACENE
- Bromobenzanthracene
- AR-E 4 7-BROMOBENZ(A)ANTHRACENE
- 7-Bromobenz[a]anthracene
- 7-Bromobenz[a]anthracene >
- Benz[a]anthracene, 7-bromo-
- 7-bromobenzo[a]anthracene
- 7-Bromotetraphene
- 32795-84-9
- C18H11Br
